The caspase10 encodes an initiating caspase that plays an important role in the maintaining the cellular homeostasis by regulating the steps involved in the immune response and cell death. We investigated the expression of caspase10 during the different developmental stages and in olive flounder tissues. Caspase10 increased in the late stage of the formation of immune tissue, and high expression was observed in the gills, kidney, skin, and spleen. The current study analyzed the expressional changes of caspase10 in olive flounder infected with viral hemorrhagic septicemia virus (VHSV). One of the major causes of mass mortality, VHSV infection in olive flounder attributes to significant expression of caspase10 in the gills, spleen, skin, and kidneys. The results indicate a close association of caspase10 expression with the immune response to VHSV infection in olive flounder. The observations could form the basis data for exploration of other fish immune system.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576969 | PMC |
| http://dx.doi.org/10.12717/DR.2020.24.3.187 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development and Application of PSCPL13 Probiotics in Olive Flounder () Farming.
Microorganisms
January 2025
Laboratory of Veterinary Pharmacokinetics, Institute for Veterinary Biomedical Science, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.
Aquaculture has grown significantly, contributing to global food security and sustainability; however, intensified fish farming has increased disease susceptibility and antibiotic resistance. This study assessed the probiotic potential of PSCPL13 (hereafter, PSCPL13), isolated from the intestines of Japanese eels, for enhancing the health of olive flounder. After screening 16 isolates, PSCPL13 was selected because of its potential broad-spectrum antibacterial activity against many pathogens, such as and .
View Article and Find Full Text PDFParentage Verification and Segregation Distortion Patterns of Microsatellite Markers in Olive Flounder () Full-Sib Families.
Animals (Basel)
January 2025
Faculty of Fisheries Life Sciences, Pukyong National University, Nam-Gu, Busan 48513, Republic of Korea.
Microsatellite markers are widely used in aquaculture for genetic analysis and breeding programs, but challenges such as segregation distortion and allelic instability can impact their effectiveness in parentage verification and inheritance studies. This study evaluated 15 microsatellite loci in seven experimental olive flounder () families bred through 1:1 full-sibling crosses, assessing their utility for accurate parentage and inheritance stability. Parentage assignments were conducted within an expanded pool of 647 candidate parents (including the actual 14 parents), encompassing both closely related and moderately distant individuals.
View Article and Find Full Text PDFReview of Cadmium Bioaccumulation in Fish Exposed to Cadmium.
Toxics
December 2024
Department of Marine Life Science, Jeju National University, Jeju 63243, Republic of Korea.
Cadmium (Cd) is a highly toxic substance in the aquatic ecosystem, which can represent a high risk to fish. Fish are exposed to heavy metals through waterborne and dietary pathways, some of which are absorbed by the body and can accumulate in specific tissues without being eliminated. The accumulation varies depending on several factors such as dose, exposure route, exposure time, metal types, and biological status of the fish, and environmental parameters such as DO, salinity, pH, and metal speciation.
View Article and Find Full Text PDFIdentification and characterization of CD83 and CD276 as markers of dendritic cells in olive flounder (Paralichthys olivaceus).
Fish Shellfish Immunol
January 2025
Department of Marine Biology & Aquaculture, College of Marine Science, Gyeongsang National University, 455, Tongyeong, 650-160, Republic of Korea. Electronic address:
Dendritic cells (DCs) play a pivotal role in activating naïve T-cells and bridging innate and adaptive immunity. This study aimed to identify and characterize CD83 and CD276 as potential markers for DCs in olive flounder (Paralichthys olivaceus). Specific antibodies against these markers were developed and used to analyze their distribution in peripheral blood leukocytes (PBLs) and intestinal tissues.
View Article and Find Full Text PDFField-based safety evaluation of rVHSV-GΔTM in aquaculture and verification of vaccine efficacy through freeze-dried prototyping in olive flounder.
Fish Shellfish Immunol
January 2025
Department of Biological Sciences, Kongju National University, Gongju 32588, South Korea. Electronic address:
Single-cycle viruses hold great promise as fish viral vaccines due to their high protective efficacy. Although the efficacy of the vaccine in olive flounder and rainbow trout has been proven through previous research, safety must be additionally proven considering the environment of use for commercialization. This study comprehensively assesses the safety of rVHSV-GΔTM and its impact on both the host and the surrounding environment, including the coastal habitat of nearby species and seawater.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!