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http://dx.doi.org/10.1016/j.drugalcdep.2020.108359 | DOI Listing |
Alzheimers Dement
December 2024
University of Southern California, San Diego, USA.
Background: Recruitment of demographically diverse participants into Alzheimer's disease (AD) clinical trials, encompassing both screening and randomization, remains a consistent and persistent challenge contributing to underrepresentation of certain groups. Despite the exciting prospects of identifying therapeutic interventions for biomarker-eligible, cognitively unimpaired individuals, these studies grapple with the inherent complexities of AD trials coupled with intricate and time-consuming screening processes. Addressing this the issue of underrepresentation necessitates concerted and intentional efforts that prioritize inclusivity and equitable access to enroll adults meeting study criteria, reflecting the demographic and social diversity of North America.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Virginia, Charlottesville, VA, USA.
Background: For care of persons with dementia (PWDs), the healthcare system relies on informal care partners (CPs), who are disproportionately at risk of detrimental health outcomes. Psychosocial interventions, including via telehealth, have been shown to buffer against negative outcomes and improve CPs' ability to provide care. We aimed to develop and pilot an evidence-informed CP intervention using in-person and telehealth modalities.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Wisconsin Alzheimer's Institute, University of Wisconsin - Madison, Madison, WI, USA.
Community Health Workers (CHWs), also known as Promotores de Salud expand health equity to underserved and hard-to-reach communities by providing increased access to healthcare and support services for caregivers and persons living with dementia (PLWD). CHWs have been particularly useful in supporting Hispanic/Latino communities, who are 1.5 times more likely to develop Alzheimer's Disease and related dementias than non-Hispanic whites and are less likely to access support services due to language and cultural barriers.
View Article and Find Full Text PDFIntroduction: Alzheimer's disease is the most common and costly neurodegenerative disease worldwide. Early studies of helmet-based 40 Hz light therapy have demonstrated safety and early efficacy in targeting the pathophysiologic characteristics of Alzheimer's disease. This intervention has shown slowing and even reversal of disease progression.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Henry Ford Health, Detroit, MI, USA.
Introduction: Alzheimer's disease is the most common and costly neurodegenerative disease worldwide. Early studies of helmet-based 40 Hz light therapy have demonstrated safety and early efficacy in targeting the pathophysiologic characteristics of Alzheimer's disease. This intervention has shown slowing and even reversal of disease progression.
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