The Importance of Critical Life Events During Childhood for the Mental Health of Adolescents - Results of a 10-Year Catamnesis This longitudinal study examines the influence of critical life events in childhood on mental disorders in childhood and adolescence. It includes parental mental disorders and parenting behavior as mediators. The review is carried out using structural equation models, separately for maternal and paternal mediators. The sample consisted of 249 families examined at six measurement points (pre to FU10); the average age of the children was 4 years, that of the adolescents 10 years later thus 14 years (FU10). Information on critical life events was collected based on a defined list. In the case of mothers, the influence of critical life events on mental disorders in childhood is completely mediated by the mental health of the mother and their dysfunctional parenting. The mediation effect of fathers' mental health is significantly less than that of the mothers (partial mediation), while their parenting behavior showed no mediating influence. Mental disorders in adolescence can be predicted primarily through mental disorders in childhood. There are no significant differences between internalizing and externalizing disorders. Parental mental health and parenting behavior, in particular of the mother, provide concrete starting points for prevention and intervention programs. Future studies should include mothers and fathers alike. Especially the role of fathers should be examined more closely.
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http://dx.doi.org/10.1024/1422-4917/a000759 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Chinese Academy of Sciences Key Laboratory of Tropical Marine Bio Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, Guangdong Provincial Observation and Research Station for Coastal Upwelling Ecosystem, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 511458, China.
Rotation of the bacterial flagellum, the first identified biological rotary machine, is driven by its stator units. Knowledge gained about the function of stator units has increasingly led to studies of rotary complexes in different cellular pathways. Here, we report that a tetrameric PilZ family protein, FlgX, is a structural component underneath the stator units in the flagellar motor of .
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Department of Psychiatry, Yongin Severance Hospital, Yongin, Republic of Korea.
Background: The COVID-19 pandemic has accelerated the digitalization of modern society, extending digital transformation to daily life and psychological evaluation and treatment. However, the development of competencies and literacy in handling digital technology has not kept pace, resulting in a significant disparity among individuals. Existing measurements of digital literacy were developed before widespread information and communications technology device adoption, mainly focusing on one's perceptions of their proficiency and the utility of device operation.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia, Hohhot, China.
Rationale: The occurrence of refractory small cell lung cancer (rSCLC) with pancreatic metastasis is a relatively rare clinical condition, which is typically accompanied by a poor prognosis and rapid disease progression.
Patient Concerns: A 65-year-old male farmer from China was diagnosed with limited-stage small cell lung cancer (SCLC) 8 months ago. Following 6 cycles of EP chemotherapy, the patient's tumor response showed partial relief.
Medicine (Baltimore)
January 2025
Precision Medical Center, Wuhan Childrens Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China.
Understanding the differences between children with severe and non-severe types of neonatal pneumonia is crucial for clinical treatment and disease management. In this study, we retrospectively analyzed the clinical data of infants with neonatal pneumonia diagnosed as respiratory syncytial virus infection at Wuhan Children's Hospital between December 1, 2022 and November 30, 2023. Further, the recruited subjects were categorized into severe and non-severe groups based on the severity score.
View Article and Find Full Text PDFVet Med Sci
January 2025
Veterinary Clinic for Reproductive Medicine and Neonatology, Justus-Liebig University of Giessen, Giessen, Hessen, Germany.
Background: Sheep's tail docking is a widespread practice, which is banned or critically discussed in some countries to improve animal welfare.
Objective: The aim was to determine the influence of breeding for short-tailedness (ST) or long-tailedness (LT) in sheep on the development of reproduction parameters and lamb performance.
Method: One hundred forty-nine ewes were mated with four rams according to tail length.
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