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Comment on: Testosterone deficiency in men with end stage renal disease and kidney transplantation: a narrative review.
Int J Impot Res
January 2025
Department of Urology, Urgup State Hospital, Nevsehir, Turkey.
Effect of bicalutamide on serum total testosterone concentration in transgender adults: a case series.
Ther Adv Endocrinol Metab
December 2024
Trans Health Research Group, Department of Medicine, University of Melbourne, Parkville, VIC 3052, Australia.
Background: There is interest in repurposing bicalutamide for gender-affirming hormone therapy, but little data regarding efficacy and safety in the transgender population.
Objectives: To determine the effect of bicalutamide on serum total testosterone concentrations and liver function. Given bicalutamide is a pure androgen receptor antagonist, we hypothesized that serum total testosterone concentrations would be higher than the cisgender female reference range and those recommended for transgender individuals in consensus guidelines.
Reply to Editorial Comment on "Castration Levels of Testosterone Results in Atrophy of Androgen-sensitive Perineal Muscles: A Potential Biomarker for Male Hypogonadism".
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Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Neurobiological stress markers in educational research: A systematic review of physiological insights in health science education.
Trends Neurosci Educ
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Center for Medical Education, Ruhr-University Bochum, 44801 Bochum, Germany.
Background: Traditional self-reported measures in health science education often overlook the physiological processes underlying cognitive and emotional responses.
Purpose: This review aims to analyze the frequency, sensitivity, and utility of physiological markers in understanding cognitive and emotional dynamics in learning environments.
Methods: A systematic PubMed search identified 156 records, with 13 studies meeting inclusion criteria.
The relation between testosterone replacement therapy (TRT) and anterior cruciate ligament injury risk has garnered attention in recent orthopaedic research. With TRT's popularity on the rise, understanding its potential musculoskeletal risks is important for orthopaedic and sports medicine providers. Whereas some studies suggest an association, confounding variables such as activity level, number of hours of sports participation, dosing variations, physiological versus supraphysiological levels of testosterone, and individual patient characteristics may influence outcomes.
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