AI Article Synopsis
- The study evaluated the effectiveness of buprenorphine replacement taper therapy for heroin dependence in a psychiatric hospital in Japan, using a review of medical records from 106 patients.
- The results demonstrated significant improvements in reducing withdrawal symptoms, increasing detox completion rates, and shortening hospital stays compared to conventional treatments.
- However, there was an observed increase in readmission rates, indicating a need for ongoing maintenance therapy for individuals after detoxification.
Article Abstract
Aim: We assessed the efficacy of buprenorphine replacement taper therapy in a psychiatric hospital in Japan.
Methods: Based on the medical records, a retrospective analysis was performed to evaluate the outcomes of buprenorphine replacement taper therapy in 106 subjects with heroin dependence.
Results: We found that replacement and taper therapy with buprenorphine could significantly reduce withdrawal symptoms during detoxification. In addition, the completion rate of detoxification was significantly improved and the length of hospital stay was significantly reduced relative to those who received conventional treatment without buprenorphine. However, the readmission rate increased after the introduction of detoxication therapy with buprenorphine.
Conclusion: The present findings suggest not only the efficacy and safety of buprenorphine replacement and taper therapy, but also the requirement for maintenance therapy for individuals with heroin dependence.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722651 | PMC |
| http://dx.doi.org/10.1002/npr2.12147 | DOI Listing |
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