Sn(IV) -confused porphyrins as photosensitizer dyes for photodynamic therapy in the near IR region.

Dalton Trans

Institute for Nanotechnology Innovation. Department of Chemistry, Rhodes University, Makhanda, South Africa.

Published: November 2020

The utility of Sn(iv) N-confused porphyrin (SnNCP) for use as photosensitizer dyes in photodynamic therapy is investigated. SnNCP has an unusually high singlet oxygen quantum yield of 0.72 in DMSO. IC50 values of 1.6 and 12.8 μM were obtained against MCF-7 cells upon irradiation with 660 and 780 nm LEDs.

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http://dx.doi.org/10.1039/d0dt03296dDOI Listing

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