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Newborns with microcephaly in Brazil and potential vertical transmission of Oropouche virus: a case series.
Lancet Infect Dis
October 2024
Department of Arbovirology and Hemorrhagic Fever, Evandro Chagas Institute, Ananindeua, Pará, Brazil. Electronic address:
Background: Oropouche fever, an orthobunyavirus disease endemic in Brazilian Amazon, has caused many febrile epidemics. In 2024, an epidemic of Oropouche fever spread in Brazil, with more than 7930 cases reported between Jan 1 and Aug 31. Infections in pregnant people have suggested the possibility of negative fetal consequences, therefore we tested newborns with microcephaly for known congenital pathogens and Oropouche virus (OROV).
View Article and Find Full Text PDFNeurodevelopmental Outcomes in Children Vertically Exposed to Chikungunya Virus: A Two Years Follow-up Study.
Pediatr Infect Dis J
September 2024
From the Maternal and Child Department, School of Medicine, Universidade Federal Fluminense.
Objectives: To monitor by the first 24 months of life, children born to mothers with laboratory evidence of chikungunya virus (CHIKV) infection during pregnancy or up to 8 weeks before it, and to describe abnormalities in head circumference (HC), auditory and ophthalmological assessments and neuroimaging tests during the follow-up period.
Method: This is a observational, descriptive, longitudinal and prospective study of children born to mothers who had a rash and a positive test for CHIKV during pregnancy or up to 8 weeks before it. They were admitted between November 2015 and May 2019 in the outpatient multidisciplinary clinic to investigate acute exanthematous disease.
Neuroinvasion of emerging and re-emerging arboviruses: A scoping review.
SAGE Open Med
May 2024
Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, București, Romania.
Background: Arboviruses are RNA viruses and some have the potential to cause neuroinvasive disease and are a growing threat to global health.
Objectives: Our objective is to identify and map all aspects of arbovirus neuroinvasive disease, clarify key concepts, and identify gaps within our knowledge with appropriate future directions related to the improvement of global health.
Methods: : A scoping review of the literature was conducted using PubMed, Scopus, ScienceDirect, and Hinari.
Design, development, and validation of multi-epitope proteins for serological diagnosis of Zika virus infections and discrimination from dengue virus seropositivity.
PLoS Negl Trop Dis
April 2024
Laboratório de Virologia Básica e Aplicada, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Zika virus (ZIKV), an arbovirus from the Flaviviridae family, is the causative agent of Zika fever, a mild and frequent oligosymptomatic disease in humans. Nonetheless, on rare occasions, ZIKV infection can be associated with Guillain-Barré Syndrome (GBS), and severe congenital complications, such as microcephaly. The oligosymptomatic disease, however, presents symptoms that are quite similar to those observed in infections caused by other frequent co-circulating arboviruses, including dengue virus (DENV).
View Article and Find Full Text PDFClinical manifestations of dengue, Zika and chikungunya in the Pacific Islands: A systematic review and meta-analysis.
Rev Med Virol
March 2024
Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia.
Dengue, Zika and chikungunya outbreaks pose a significant public health risk to Pacific Island communities. Differential diagnosis is challenging due to overlapping clinical features and limited availability of laboratory diagnostic facilities. There is also insufficient information regarding the complications of these arboviruses, particularly for Zika and chikungunya.
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