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Translation, cross-cultural adaptation, and psychometric properties of the Finnish version of the Malocclusion Impact Questionnaire (MIQ).
Acta Odontol Scand
January 2025
Research Unit of Population Health, University of Oulu, Oulu, Finland; The Wellbeing Service County of North Ostrobothnia, Pohde, Finland; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
Objectives: This study aimed to translate and adapt the Malocclusion Impact Questionnaire (MIQ) into Finnish; to estimate its psychometric properties when applied to Finnish adolescents; and to estimate the effect of demographic characteristics on the perceived impact of malocclusion.
Methods: The Finnish version of MIQ (MIQ-Fi) was established through translation, back-translation, and a pilot study. Psychometric properties were estimated using factorial validity (confirmatory factor analysis [CFA]), convergent validity (Average Variance Extracted [AVE]), and reliability (αordinal and ω).
A Deep Learning Framework for Automated Classification and Archiving of Orthodontic Diagnostic Documents.
Cureus
December 2024
Department of Orthodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, IRN.
Background Orthodontic diagnostic workflows often rely on manual classification and archiving of large volumes of patient images, a process that is both time-consuming and prone to errors such as mislabeling and incomplete documentation. These challenges can compromise treatment accuracy and overall patient care. To address these issues, we propose an artificial intelligence (AI)-driven deep learning framework based on convolutional neural networks (CNNs) to automate the classification and archiving of orthodontic diagnostic images.
View Article and Find Full Text PDFDental and oral health assessments in the German National Cohort (NAKO).
BMC Oral Health
January 2025
Department of Restorative Dentistry, Periodontology and Endodontology, University Medicine Greifswald, Greifswald, Germany.
Background: Despite considerable improvements in oral health in recent decades, caries and periodontitis are still widespread, ranking among the most prevalent diseases worldwide and requiring future research. The German National Cohort (NAKO Gesundheitsstudie, NAKO) is a large-scaled, multidisciplinary, nationwide, multi-centre, population-based, prospective cohort study with oral examinations that aims to provide a resource to study risk factors for major diseases. The aim of the present article is to provide the methodological background, to report on the data quality, and to present initial results of the oral examinations.
View Article and Find Full Text PDFInvestigating the Multigenerational Effects of DDT Residues Exposure on Dental Development in Wistar Rats.
Environ Toxicol Pharmacol
January 2025
Department of Orthodontics, University Hospital Bonn, Medical Faculty, Welschnonnenstr. 17, 53111, Bonn, Germany. Electronic address:
The pesticide Dichlorodiphenyltrichloroethane (DDT) and its degradation by-products (Dichlorodiphenyldichloroethane-DDD and dichlorodiphenyldichloroethylene-DDE) are health concerns. This study aimed to investigate the impact of multigenerational exposure to traces of DDD and DDE on odontogenesis Wistar rats were allocated in 4 groups over 2 generations (F1 and F2). Water was provided ad libitum throughout the animal's life groups: control - natural water; DDD - 0.
View Article and Find Full Text PDFDental manifestations of hypophosphatasia: translational and clinical advances.
JBMR Plus
February 2025
Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, 43210, United States.
Hypophosphatasia (HPP) is an inherited error in metabolism resulting from loss-of-function variants in the gene, which encodes tissue-nonspecific alkaline phosphatase (TNAP). TNAP plays a crucial role in biomineralization of bones and teeth, in part by reducing levels of inorganic pyrophosphate (PP), an inhibitor of biomineralization. HPP onset in childhood contributes to rickets, including growth plate defects and impaired growth.
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