Incremental sheet metal forming can manufacture various sheet metal products without a dedicated punch and die set. In this study, we developed a two-stage incremental forming process to decrease shape errors in the conventional incremental forming process. The forming process was classified into the first single point incremental forming (1st SPIF) process for forming a product and the counter single point incremental forming (counter SPIF) process to decrease shape error. The counter SPIF gives bending deformation in the opposite direction. Furthermore, the counter SPIF compensates for shape errors, such as section deflection, skirt spring-back, final forming height, and round. The tool path of the counter SPIF has been optimized through a relatively simple optimization method by modifying the tool path of the previous step. The tool path of the 1st SPIF depends on the geometry of the product. An experiment was performed to form a circular cup shape to verify the proposed tool path of the 1st and counter SPIF. The result confirmed that the shape error decreased when compared to the conventional SPIF. For the application, the ship-hull geometry was adopted. Experimental results demonstrated the feasibility of the two-stage incremental forming process.
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http://dx.doi.org/10.3390/ma13214719 | DOI Listing |
Sci Rep
January 2025
School of Computer Science and Technology, Donghua University, Shanghai, 201620, China.
Extracting high-order abstract patterns from complex high-dimensional data forms the foundation of human cognitive abilities. Abstract visual reasoning involves identifying abstract patterns embedded within composite images, considered a core competency of machine intelligence. Traditional neuro-symbolic methods often infer unknown objects through data fitting, without fully exploring the abstract patterns within composite images and the sequential sensitivity of visual sequences.
View Article and Find Full Text PDFValue Health Reg Issues
January 2025
Department of Pharmaceutical Sciences, Faculty of Pharmacy/Postgraduate Nursing Program, Federal University of Juiz de Fora, Minas Gerais, Brazil. Electronic address:
Objectives: To describe the characteristics of the demands for health technologies submitted to the Brazilian Government.
Methodology: A descriptive analysis was carried out by surveying the reports produced by the National Committee for the Incorporation of Health Technologies since its creation in Brazil until 2023. The extracted data were tabulated in 3 domains: identification of demand, epidemiological profile of the disease, and clinical evidence and economic assessment.
CNS Drugs
February 2025
Innovative Medicines and Global Clinical Development, Teva Branded Pharmaceutical Products R&D, Inc., West Chester, PA, USA.
Background: Huntington disease (HD) is a progressive neurodegenerative disease that causes psychiatric and neurological symptoms, including involuntary and irregular muscle movements (chorea). Chorea can disrupt activities of daily living, pose safety issues, and may lead to social withdrawal. The vesicular monoamine transporter 2 inhibitors tetrabenazine, deutetrabenazine, and valbenazine are approved treatments that can reduce chorea.
View Article and Find Full Text PDFBiol Trace Elem Res
January 2025
School of Biological Sciences, Monash University, Melbourne, VIC, 3800, Australia.
As teeth develop, their mineralised composition is a bio-recorder of diet, environment, and growth. High-resolution elemental mapping provides a tool to reveal records of life history within teeth. The relative concentrations of a range of trace elements change between in utero development, birth, and weaning in eutherian mammals.
View Article and Find Full Text PDFACS Nano
January 2025
School of Materials Science and Engineering, China University of Petroleum (East China), Qingdao 266580, Shandong, China.
Core-shell structures demonstrate superior capability in customizing properties across multiple scales, offering valuable potential in catalysis, medicine, and performance materials. Integrating functional nanoparticles in a spatially controlled manner is particularly appealing for developing sophisticated architectures that support heterogeneous characteristics and tandem reactions. However, creating such complex structures with site-specific features remains challenging due to the dynamic microenvironment during the shell-forming process, which considerably impacts colloidal particle assembly.
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