Acute severe colitis is a medical emergency and requires prompt treatment with intravenous steroids. Infliximab is typically used as rescue therapy in those who fail to respond to corticosteroids. This article outlines the altered pharmacokinetics of infliximab in acute severe UC and summarised the latest published data surrounding accelerated infliximab dosing.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569519PMC
http://dx.doi.org/10.1136/flgastro-2020-101407DOI Listing

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