eradication improved the Kyoto classification score on endoscopy.

Background And Aim: Endoscopy-based Kyoto classification predicts the risk of infection and gastric cancer; however, the change in score following eradication remains unknown. We retrospectively compared the Kyoto score before and after eradication.

Methods: positive patients who underwent baseline esophagogastroduodenoscopy (EGD), successful eradication, and surveillance EGD were enrolled. The Kyoto score is a sum of scores for atrophy (Kimura-Takemoto atrophic-border classification none or C1: 0, C-II or C-III: 1, O-I to O-III: 2), intestinal metaplasia (none: 0, antrum: 1, corpus and antrum: 2), enlarged folds (absence: 0, presence: 1), nodularity (absence: 0, presence: 1), and diffuse redness (none: 0, mild: 1, severe: 2) and ranges from 0 to 8.

Results: Eighty-three patients (mean age: 54.9 years; 65.1% women) were enrolled. The mean duration from successful eradication to surveillance EGD was 256 days. The Kyoto score significantly decreased from 3.90 to 2.78 following eradication ( < 0.001). Scores for endoscopic atrophy (from 1.43 to 1.46, = 0.638) and endoscopic intestinal metaplasia (from 0.53 to 0.47, = 0.543) did not change; however, there was significant improvement in the scores for enlarged folds (from 0.14 to 0.00, = 0.002), nodularity (from 0.18 to 0.04, = 0.002), and diffuse redness (from 1.61 to 0.82,  < 0.001).

Conclusion: The Kyoto classification score decreased following eradication. A decrease in the scores for enlarged folds, nodularity, and diffuse redness contributed to the decrease in Kyoto score.