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| http://dx.doi.org/10.3389/fpsyg.2020.02243 | DOI Listing |
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Should cancer pain still be considered a separate category alongside acute pain and chronic non-cancer pain? Reflections on ICD-11.
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May 2024
Pain and Rehabilitation Center, and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Introduction: Traditionally, cancer pain has often been viewed as an independent third major category in pain medicine alongside acute pain and chronic non-cancer pain. However, the new chronic pain category MG30 in the eleventh version of International Classification of Diseases (ICD-11) includes cancer-related pain as one of its seven subgroups. In light of this, the aim of the paper is to investigate whether the traditional trichotomy should be replaced by a dichotomy between acute pain and chronic pain, cancer-related pain being part of both groups depending on the duration of pain.
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April 2024
Texas A&M University, Department of Psychological & Brain Sciences, 4235 TAMU, College Station, TX 77843-4235, United States. Electronic address:
The control of attention was long held to reflect the influence of two competing mechanisms of assigning priority, one goal-directed and the other stimulus-driven. Learning-dependent influences on the control of attention that could not be attributed to either of those two established mechanisms of control gave rise to the concept of selection history and a corresponding third mechanism of attentional control. The trichotomy framework that ensued has come to dominate theories of attentional control over the past decade, replacing the historical dichotomy.
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Department of Psychology, University of Windsor.
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View Article and Find Full Text PDFThe trichotomy of HER2 expression confers new insights into the understanding and managing for breast cancer stratified by HER2 status.
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Human epidermal growth factor receptor 2 (HER2) is a tyrosine kinase receptor that plays a carcinogenic role in breast cancer (BC) through gene amplification, mutation, or overexpression. Traditional methods of HER2 detection were divided into positive (immunohistochemistry (IHC) 3+/fluorescence in situ hybridization (FISH) amplification) and negative (IHC 2+/FISH-, IHC 1+, IHC 0) according to the dichotomy method. Anti-HER2-targeted therapies, such as trastuzumab and pertuzumab, have significantly improved the prognosis of HER2-positive patients.
View Article and Find Full Text PDFA Fisher-KPP Model with a Nonlocal Weighted Free Boundary: Analysis of How Habitat Boundaries Expand, Balance or Shrink.
Bull Math Biol
January 2022
Department of Mathematical and Statistical Sciences, University of Alberta, Edmonton, AB, T6G 2G1, Canada.
In this paper, we propose a novel free boundary problem to model the movement of single species with a range boundary. The spatial movement and birth/death processes of the species found within the range boundary are assumed to be governed by the classic Fisher-KPP reaction-diffusion equation, while the movement of a free boundary describing the range limit is assumed to be influenced by the weighted total population inside the range boundary and is described by an integro-differential equation. Our free boundary equation is a generalization of the classical Stefan problem that allows for nonlocal influences on the boundary movement so that range expansion and shrinkage are both possible.
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