Marginal zone lymphomas (MZLs) are rare and indolent subtypes of non-Hodgkin lymphomas, and their clinical behaviours are heterogeneous. The aim of this study was to evaluate the clinical and prognostic characteristics of MZL. In this multicentre retrospective study, we analyzed demographical, clinical and prognostic features of 64 MZL patients. The median age was 54.0 and 78.1% of the patients had extra-nodal disease at presentation. Most of the patients were treated with chemotherapy. The 5 years and 10 years overall survival (OS) rates were 74.5% and 62.1%, respectively. The analysis of factors associated with OS showed that ECOG performance score was an important prognostic factor, with 133.0 months (95% CI 49.3-216.5) versus 18.0 months (95% CI 12.1-23.7) for ECOG 0-1 and 2-3, respectively (= 0.011). Prognosis of MZL is favorable and ECOG performance score was found associated with OS. Further detailed studies with large patient numbers are needed to clarify the clinical features and treatment management of MZLs.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573056PMC
http://dx.doi.org/10.1007/s12288-020-01257-0DOI Listing

Publication Analysis

Top Keywords

demographical clinical
8
clinical features
8
marginal zone
8
zone lymphomas
8
retrospective study
8
clinical prognostic
8
ecog performance
8
performance score
8
features marginal
4
lymphomas retrospective
4

Similar Publications

Background Ankle fractures are one of the most common presentations in orthopaedic surgery and represent the third most frequent musculoskeletal injury in the elderly population. Syndesmotic injuries can be associated with ankle fractures, and surgical intervention is critical in these injuries to restore stability and prevent long-term disability. Traditionally, syndesmotic screw fixation has been the standard treatment for acute traumatic syndesmotic injuries, but controversies regarding this fixation method remain.

View Article and Find Full Text PDF

Development of a web-based tool to assess daily rating of perceived exertion in agility dogs.

Front Vet Sci

December 2024

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.

Objective: To develop a web-based tool for daily use by agility handlers to log rating of perceived exertion (RPE) for dogs as an aid in quantifying daily exercise and training load and to improve training and conditioning strategies.

Procedures: Focus group meetings with small groups of handlers were conducted via internet-based video conferencing using a semi-structured interview format. Meeting notes were coded for reflexive thematic analysis.

View Article and Find Full Text PDF

Background: Although several National Data Registries for Congenital Heart Disease (CHD) exist, few are comprehensive and contemporary. A National Australian CHD Registry has been developed that aims to redress this by creating the first comprehensive data collection for CHD children and adults, initially across Australia.

Methods: We defined and collected a minimum dataset of demographics, diagnoses, and procedures from people with CHD presenting at participating quaternary CHD services Australia-wide.

View Article and Find Full Text PDF

Background: As artificial intelligence (AI) continues to permeate various sectors including healthcare, understanding its impact on nursing students' attitudes and intentions to use is crucial. To examine the association of AI ethical awareness, attitudes, anxiety, and intention-to-use AI technology among Jordanian nursing students.

Method: A descriptive, cross-sectional design was used.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!