AI Article Synopsis

  • A child with bilateral tibial fractures developed significant hematomas and experienced four days of fever, shown by high C-reactive protein and sedimentation rates.
  • As infections and blood clots were ruled out, the fever was linked to the hematomas.
  • The inflammation and fever were likely caused by the release of pyrogenic cytokines from the hematomas, which are known to trigger a noninfectious fever response.

Article Abstract

After incurring bilateral tibial fractures and developing sizable hematomas at the trauma sites, a child experienced 4 days of fever with an elevated C-reactive protein level and sedimentation rate. As thrombotic and infectious etiologies were ruled out, the patient's febrile and inflammatory response was likely attributable to hematoma formation. Hematomas are a recognized cause of noninfectious fever. Local release of pyrogenic cytokines within the hematoma may be the source for elevation in temperature and inflammatory markers.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549963PMC
http://dx.doi.org/10.1080/08998280.2020.1783750DOI Listing

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