After incurring bilateral tibial fractures and developing sizable hematomas at the trauma sites, a child experienced 4 days of fever with an elevated C-reactive protein level and sedimentation rate. As thrombotic and infectious etiologies were ruled out, the patient's febrile and inflammatory response was likely attributable to hematoma formation. Hematomas are a recognized cause of noninfectious fever. Local release of pyrogenic cytokines within the hematoma may be the source for elevation in temperature and inflammatory markers.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549963 | PMC |
http://dx.doi.org/10.1080/08998280.2020.1783750 | DOI Listing |
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