AI Article Synopsis
- Recent studies show that hoarseness can occur in children with Kawasaki disease (KD), a condition that affects the heart and blood vessels.
- In a study involving 865 KD patients in Latin America, 11.6% were found to have hoarseness, particularly in younger children with lower blood counts.
- The findings suggest that hoarseness is a common symptom in acute KD and may signal underlying inflammation or anemia in affected individuals.
Article Abstract
Background: Recently, hoarseness affecting the supraglottic structure has been reported in Kawasaki disease (KD). The objective of this study was to characterize the frequency of hoarseness in acute KD patients in Latin America.
Methods: We used prospective data from the multinational Red de Enfermedad de Kawasaki en America Latina (REKAMLATINA) network. A total of 865 patients from 20 countries were enrolled during the 3 year study period. Data on hoarseness were available in 858 (99.2%) patients. The clinical and laboratory characteristics between hoarse and non-hoarse KD were compared.
Results: Hoarseness was documented in 100 (11.6%) patients. Hoarse patients were younger than those with KD without hoarseness (median age 18 vs 26 months; P = 0.002) and presented with lower hemoglobin (10.7 g/dL vs 11.3 g/dL; P = 0.040) and hematocrit levels (32% vs 33%, P = 0.048).
Conclusions: Hoarseness was found to be prevalent as a presenting sign of acute KD in younger children. Anemia may indicate the presence of active inflammation.
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| http://dx.doi.org/10.1111/ped.14521 | DOI Listing |
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