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Reissuing the sigma receptors for SARS-CoV-2. | LitMetric

Reissuing the sigma receptors for SARS-CoV-2.

J Clin Neurosci

Department of Psychiatry, Bakirkoy Prof Mazhar Osman Training and Research Hospital for Psychiatry, Neurology, and Neurosurgery, Istanbul, Turkey.

Published: October 2020

AI Article Synopsis

  • Receptor binding plays a key role in determining which tissues SARS-CoV-2 can infect.
  • SARS-CoV-2 shows neurotropism, meaning it can infect the central nervous system (CNS) by interacting with various receptors.
  • Sigma receptors may play a role in how SARS-CoV-2 transmits within neurons.

Article Abstract

• Receptor binding is a major determinant of tissue tropism for SARS-CoV-2. • Neurotropism of SARS-CoV-2 associated with a broad range of receptors in the central nervous system (CNS). • Sigma receptors may be involved in the neuronal transmission of SARS-CoV-2.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418634PMC
http://dx.doi.org/10.1016/j.jocn.2020.08.014DOI Listing

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