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http://dx.doi.org/10.1038/s41419-020-02933-9 | DOI Listing |
Mol Biol Rep
May 2023
Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Cell Death Dis
October 2020
School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
J Obstet Gynaecol
October 2019
Department of Medical Biochemistry and Clinical Biochemistry (Firat Hormones Research Group), Medical School, Firat University, Elazig , Turkey.
Pre-eclampsia is multisystem metabolic diseases, commonly accompanied by hypertension and proteinuria, which are among the important causes of maternal and perinatal mortality and morbidity worldwide. In a pre-eclampsia animal model study in the last year, Elabela (ELA) infusion was reported to correct hypertension and proteinuria and to normalise the birth weights of the offspring. Therefore, our main goal in this human study is to compare ELA, apelin (APLN) and nitric oxide (NO) levels in the maternal blood of pregnant women with pre-eclampsia and severe pre-eclampsia and in their newborns' venous-arterial cord blood with maternal blood of healthy pregnant women and their newborns' venous-arterial cord blood.
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