COVID-19-Associated Systemic Thromboembolism: A Case Report and Review of the Literature.

Cardiorenal Med

Baylor University Medical Center, Baylor Scott and White Heart and Vascular Institute, Texas A&M College of Medicine, Dallas, Texas, USA.

Published: December 2020

Introduction: Coronavirus disease 2019 (COVID-19) is a pandemic that has affected >188 countries, involved >24 million people, and caused >840,000 deaths. COVID-19, in its severe form, presents as acute respiratory distress syndrome (ARDS), shock, and multiorgan failure. Thrombotic microangiopathy of the lungs and kidneys has been observed in these patients. Elevated D-dimer levels have been observed in people with serious COVID-19 illness, and this could be helpful in guiding treatment with anticoagulation in these patients.

Objective: To analyze the role of anticoagulation as a treatment modality for COVID-19.

Methods: We present the unique case of a COVID-19 patient who developed sepsis, ARDS, acute kidney injury, and deep-vein thrombosis (DVT), who was deteriorating clinically. She was treated with anticoagulation.

Results: There was rapid recovery after treatment with systemic anticoagulation.

Conclusions: Systemic anticoagulation could prove to be essential in the treatment of CO-VID-19. Further studies are required to assess its role in improving long-term morbidity and mortality in these patients.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649692PMC
http://dx.doi.org/10.1159/000511800DOI Listing

Publication Analysis

Top Keywords

covid-19-associated systemic
4
systemic thromboembolism
4
thromboembolism case
4
case report
4
report review
4
review literature
4
literature introduction
4
introduction coronavirus
4
coronavirus disease
4
disease 2019
4

Similar Publications

Background: Preventing severe COVID-19 associated outcomes continues to be a priority for persons with multiple sclerosis (PwMS). We previously reported in an interim analysis that short-term reactions to the first and second SARS-CoV-2 vaccines experienced by PwMS were mostly self-limiting and similar to reactions experienced by the general population.

Objectives: First, to report short-term reactogenicity experienced by PwMS in relation to the first through fourth SARS-CoV-2 vaccines.

View Article and Find Full Text PDF

Scurvy incidence trend among children hospitalised in France, 2015-2023: a population-based interrupted time-series analysis.

Lancet Reg Health Eur

February 2025

Department of General Paediatrics, Paediatric Internal Medicine, Rheumatology and Infectious Diseases, National Reference Centre for Rare Paediatric Inflammatory Rheumatisms and Systemic Autoimmune Diseases (RAISE), Robert-Debré University Hospital, Assistance Publique-Hôpitaux de Paris, F-75019, Paris, France.

Background: Scurvy, historically rare in-high income countries, has re-emerged as an indicator of socioeconomic and dietary disparities. Limited data exist on scurvy trends among European children, particularly following socioeconomic changes since the COVID-19 pandemic. This study analysed scurvy incidence trends among French children over a nine-year period, examining potential post-pandemic increases.

View Article and Find Full Text PDF

Biological and genomic analyses of , a novel potential fungal pathogen closely related to (syn. ) and .

New Microbes New Infect

December 2024

Shanghai Institute of Infectious Disease and Biosecurity, Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, State Key Laboratory of Genetic Engineering, School of Life Science, Fudan University, Shanghai, PR China.

Article Synopsis
  • - A new species of fungus, identified from a COVID-19 patient's sputum, has been discovered, belonging to the genus *Candida*.
  • - This novel species is closely related to other known fungal pathogens but shows notable genetic differences and chromosomal rearrangements compared to them.
  • - Although it does not thrive at human body temperature, it has been found to increase in lung tissue during a mouse infection model, suggesting it may act as an opportunistic pathogen.
View Article and Find Full Text PDF

Purpose Of Review: COVID -19 associated olfactory dysfunction is widespread, yet effective treatment strategies remain unclear. This article aims to provide a comprehensive systematic review of therapeutic approaches and offers evidence-based recommendations for their clinical application.

Recent Findings: A living Cochrane review, with rigorous inclusion criteria, has so far included 2 studies with a low certainty of evidence.

View Article and Find Full Text PDF
Article Synopsis
  • * The study evaluated the effects of infusion therapy on microcirculation in sepsis patients, using advanced monitoring techniques and involving a comparison between bacterial and COVID-19-related sepsis.
  • * Results showed that patients with bacterial sepsis had worse microcirculation dysfunction and higher serum lactate levels than those with COVID-19, emphasizing the importance of monitoring microcirculation and using tools like remote photoplethysmography (rPPG) and automated capillary refill time (aCRT) in treatment.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!