Background: In dermatology, the topical application of liposomes has proven to be of therapeutic value. Many drugs encapsulated into liposomes have shown enhanced skin penetration.
Methods: Liposomes are lipid based spherical vesicles. In structure and composition, they resemble cell membrane. Because of their amphipathic nature, they can be used as carriers for hydrophilic as well as lipophilic therapeutic agents. These liposomal systems can easily get integrated with the skin lipids and maintain the desired hydration conditions to improve drug penetration and localization in the skin layers.
Results: Considering the need for topical delivery and the promising potential of liposomes, an attempt has been made to explore the recent advances of liposome-based formulations in dermatological applications.
Conclusion: This patent summarizes the recent findings of liposome-based formulations for dermal delivery of drugs.
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| http://dx.doi.org/10.2174/1872210514666201021145233 | DOI Listing |
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