AI Article Synopsis

  • Protein-losing enteropathy (PLE) is a rare disorder that can occur in patients with systemic lupus erythematosus (SLE), leading to significant health issues such as diarrhoea and hypoalbuminemia.
  • The case study describes a 59-year-old woman with SLE who experienced recurrent PLE due to different underlying conditions, including portal vein thrombosis, which improved with anticoagulants and later with immunosuppressive therapy for SLE.
  • This highlights the importance of diagnosing the specific cause of PLE in SLE patients to ensure effective treatment and management.

Article Abstract

Protein-losing enteropathy (PLE) is a rare organ disorder that can develop as a complication of systemic lupus erythematosus (SLE). Here, we report the case of a 59-year-old woman with SLE who experienced recurrent PLE resulting from different pathological conditions. The patient was diagnosed with SLE in X-14. In X-12, she was hospitalised due to persistent diarrhoea, generalised oedema, abdominal distension, dyspnoea on exertion, and hypoalbuminemia. A thrombus was noted in the superior mesenteric vein extending from the main trunk of the portal vein. She was diagnosed with PLE resulting from portal vein thrombosis caused by SLE, and her condition improved with anticoagulant therapy. In X-1, she developed diarrhoea and hypoalbuminemia again and was diagnosed with PLE associated with SLE. The symptoms promptly ameliorated with immunosuppressive therapy. Because PLE associated with SLE can be caused by various pathological conditions, appropriate therapeutic intervention based on the underlying condition is crucial.

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Source
http://dx.doi.org/10.1080/24725625.2020.1738988DOI Listing

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