AI Article Synopsis
- Cardiac arrhythmias contribute to a significant number of deaths from cardiovascular diseases globally, with metabolic factors like obesity and diabetes increasing the risk.
- Despite established links between high-fat diets and arrhythmias, the specific mechanisms behind this connection are still not fully understood, although oxidative stress is important.
- The review explores metabolic changes caused by obesity and high-fat diets, and discusses possible treatments for arrhythmias, including the use of antioxidants.
Article Abstract
Cardiac arrhythmias are responsible for many cardiovascular disease-related deaths worldwide. While arrhythmia pathogenesis is complex, there is increasing evidence for metabolic causes. Obesity, diabetes, and chronically consuming high-fat foods significantly increase the likelihood of developing arrhythmias. Although these correlations are well established, mechanistic explanations connecting a high-fat diet (HFD) to arrhythmogenesis are incomplete, although oxidative stress appears to be critical. This review investigates the metabolic changes that occur in obesity and after HFD. Potential therapies to prevent or treat arrhythmias are discussed, including antioxidants.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603089 | PMC |
| http://dx.doi.org/10.3390/antiox9101012 | DOI Listing |
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