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Response to letter to the editor re adapting lean methodology towards surgical tray rationalisation in inguinoscrotal day case surgery in the Republic of Ireland.
J Pediatr Urol
October 2023
University College Dublin, Division of Paediatric Urology, Dublin, Ireland. Electronic address:
Operational complexity versus design efficiency: challenges of implementing a phase IIa multiple parallel cohort targeted treatment platform trial in advanced breast cancer.
Trials
May 2022
Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, UK.
Article Synopsis
- Platform trials are used in cancer research to test different treatments at the same time, making the process faster and more efficient.
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An ethical analysis of UK drug policy as an example of a criminal justice approach to drugs: a commentary on the short film Putting UK Drug Policy into Focus.
Harm Reduct J
December 2020
School of Population Health Sciences, University of Bristol, Bristol, UK.
Background: Drug-related deaths in the UK are at the highest level on record-the war on drugs has failed. A short film has been produced intended for public and professional audiences featuring academics, representatives of advocacy organisations, police and policymakers outlining the problems with, and highlighting alternative approaches to, UK drug policy. A range of ethical arguments are alluded to, which are distilled here in greater depth for interested viewers and a wider professional and academic readership.
View Article and Find Full Text PDFReposition of montelukast either alone or in combination with levocetirizine against SARS-CoV-2.
Med Hypotheses
November 2020
Chichuria Institute of Medical Science & Research, Thakurpara, Chichuria, Bethuadahari-II (XVI), Nadia, West Bengal 741 126, India. Electronic address:
It has been hypothesised that antiallergic medications (AAMs) like montelukast and levocetirizine both the two bitter chloro compounds could be repurposed either alone or combinedly as an antiviral against SARS-CoV-2, like chloroquine/hydroxychloroquine (CQ/HCQ), another two bitter chloro compounds. Both AAMs and CQ/HCQ are bitter tasted chloro compounds. Depending on their these two similar physical properties and the safety and efficacy of AAMs by controlling over post viral episodes as comparing with viral inhibitory activities including SARS-CoV-2 by CQ/HCQ, a reposition of AAMs either alone/combinedly could be rationalised as an antiviral approach to nCoV.
View Article and Find Full Text PDFBreast reconstruction with immediate autologous free tissue transfer in a peri-operative COVID-19 positive patient: A case report illustrating feasibility of aftercare.
J Plast Reconstr Aesthet Surg
March 2021
Department of Plastic Surgery, Norfolk and Norwich University Hospital, Norwich, Colney Lane NR4 7UY, United Kingdom.
Globally, there has been a measured response to rationalise elective operating during the Coronavirus disease 2019 (COVID-19) pandemic. In terms of breast cancer care, this has led to a restricted provision of reconstruction with autologous free tissue transfer. A primary concern is the risk of mortality in elective surgery patients who develop COVID-19.
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