AI Article Synopsis
- * A 17-year-old male exhibited symptoms including body aches and swelling on the right side of his head, along with rapid periorbital puffiness, which scans showed to be multiple subgaleal haematomas and edema.
- * Both conditions are uncommon in sickle cell disease but can be managed conservatively rather than through surgery, as demonstrated in the case of this patient.
Article Abstract
Background: Sickle cell disease is a genetic condition frequently found in Africa and the Arabian Peninsula. Uncommon complications include subgaleal haematoma (soft head syndrome) and periorbital oedema.
Case Presentation: A 17-year-old male patient presented with body aches and progressive right parieto-temporal and frontal head swelling. Physical examination revealed puffiness of the right eye that progressed rapidly to reddish periorbital oedema sparing the extraocular muscle and pupil response to light. CT and MRI of the brain suggested multiple subgaleal haematomas (soft head syndrome) and right periorbital oedema.
Conclusion: Subgaleal haematoma (soft head syndrome) and periorbital oedema are uncommon complications of sickle cell disease. Management is conservative rather than surgical.
Learning Points: Subgaleal haematoma concurrently with periorbital oedema is a rare presentation of sickle cell disease.There are no guidelines on treatment, but the conditions in our patient resolved with conservative management.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546570 | PMC |
| http://dx.doi.org/10.12890/2020_001766 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
AlgaeSperm: Microalgae-Based Soft Magnetic Microrobots for Targeted Tumor Treatment.
Small
January 2025
School of Mechanical Engineering and Automation, Beihang University, Beijing, 100191, China.
Magnetic microrobots are significant platforms for targeted drug delivery, among which sperm-inspired types have attracted much attention due to their flexible undulation. However, mass production of sperm-like soft magnetic microrobots with high-speed propulsion is still challenging due to the need of more reasonable structure design and facile fabrication. Herein, a novel strategy is proposed for large-scale preparation of microalgae-based soft microrobots with a fully magnetic head-to-tail structure, called AlgaeSperm with robust propulsion and chemo-photothermal performance.
View Article and Find Full Text PDFA pilot study comparing three-dimensional models of tumor histopathology and magnetic resonance imaging.
Sci Rep
January 2025
Department of Otorhinolaryngology - Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, P.O. Box 263, 00029, Helsinki, Finland.
Three-dimensional (3D) modeling is often used to provide better visual understanding. This has become an everyday tool especially in medical imaging. However, modeling soft tissue histopathology in 3D is in its early stages, thus making 3D comparison between radiology and histopathology difficult.
View Article and Find Full Text PDFEvaluating the impact of a hand-crafted 3D-Printed head Model and virtual reality in skull base surgery training.
Brain Spine
December 2024
Department of Neurosurgery, University Hospital of Lausanne and University of Lausanne, 1011, Lausanne, Switzerland.
Introduction: While cadaveric dissections remain the cornerstone of education in skull base surgery, they are associated with high costs, difficulty acquiring specimens, and a lack of pathology in anatomical samples. This study evaluated the impact of a hand-crafted three-dimensional (3D)-printed head model and virtual reality (VR) in enhancing skull base surgery training.
Research Question: How effective are 3D-printed models and VR in enhancing training in skull base surgery?
Materials And Methods: A two-day skull base training course was conducted with 12 neurosurgical trainees and 11 faculty members.
Management Modalities of Mandible Fracture and Dental Trauma in Pediatric Patients During Mixed Dentition Phase: A Series of Case Study.
Case Rep Dent
January 2025
Department of Dentistry, NEIGRIHMS (North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences), Shillong, India.
The prevalence of oromaxillofacial fracture in pediatric patients is comparatively less than in adults, which could be due to several inconclusive factors, such as infrequent exposure to high-contact sports games, rash driving of vehicles and motorbikes, alcohol consumption, and fist fights for personal reasons under the influence of alcohol. More importantly, most of the time, children are under the care of their parents till they reach an age of maturity. One more thing that everyone believes even today is the elasticity nature of their bones as well as their body weight during their growing stage.
View Article and Find Full Text PDFNovel Therapeutics in Soft Tissue Sarcoma.
Cancers (Basel)
December 2024
Sarcoma Unit, The Royal Marsden Hospital and Institute of Cancer Research, London SW3 6JZ, UK.
There has been noteworthy progress in molecular characterisation and therapeutics in soft tissue sarcomas. Novel agents have gained regulatory approval by the FDA. Examples are the tyrosine kinase inhibitors avapritinib and ripretinib in gastrointestinal stromal tumours (GIST), the immune check point inhibitor atezolizumab in alveolar soft part tissue sarcoma, the γ-secretase inhibitor nirogacestat in desmoid tumours, the NTRK inhibitors larotrectinib and entrectinib in tumours with fusions, the mTOR inhibitor nab-sirolimus in PEComa, and the EZH-2 inhibitor tazemetostat in epithelioid sarcoma.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!