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| http://dx.doi.org/10.4103/ijnm.IJNM_64_20 | DOI Listing |
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Exploring the relationship between proactive inhibition and restrictive eating behaviours in severe and enduring anorexia nervosa (SE-AN).
J Eat Disord
January 2025
Centre for Research in Eating and Weight Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Background: There is a need for improved understanding of why 20-30% of individuals with anorexia nervosa (AN) develop a severe and enduring form of illness (SE-AN). Previously, we reported differences in proactive inhibition (a pre-emptive slowing of responses) in individuals with AN compared to healthy controls (after controlling for intolerance of uncertainty). The present study is a preliminary exploration of proactive inhibition in which we compared women with SE-AN with healthy comparison (HC) women and explored its association with restrictive/avoidant eating behaviours.
View Article and Find Full Text PDFGenomics-based timely detection of dengue virus type I genotypes I and V in Uruguay.
Heliyon
November 2024
Laboratorio de Virus Emergentes/reemergentes. Unidad de Virología, Departamento de Laboratorios de Salud Pública, Portugal.
This study details a genomics-based approach for the early detection of mosquito-borne pathogens, marked by Uruguay's first ever complete genomic sequencing of Dengue Virus type I genotypes I and V. This pioneering effort has facilitated the prompt identification of these genotypes within the country, enabling Uruguayan public health authorities to develop timely and effective response strategies. Further integrated into this approach is a climate-driven suitability measure, closely associated with Dengue case reports and indicative of the local climate's role in the virus's transmission in the country within the changing climate context.
View Article and Find Full Text PDFPredictive marker for response to trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer patients.
BMC Cancer
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Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-Cho, Kita-Ku, Okayama, 700-8558, Japan.
Objective: Trifluridine/tipiracil (FTD/TPI) is one of the options for late-line treatment of colorectal cancer (CRC). However, the specific patient populations that would particularly benefit from it remain unclear. This study attempted to identify predictive markers of chemotherapy efficacy with trifluridine/tipiracil (FTD/TPI), focusing on the RNA-editing enzyme adenosine deaminase acting on RNA 1 (ADAR1) expression and neutrophil-lymphocyte ratio (NLR).
View Article and Find Full Text PDFUnlocking Drivers of Country-Specific Sensitivities of Atmospheric Greenhouse Gas Accumulation: Preparing for Future Pandemic Management.
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January 2025
Water Research Centre, School of Civil and Environmental Engineering, The University of New South Wales, Sydney, New South Wales 2052, Australia.
The global atmospheric greenhouse gas (GHG) accumulation trajectory has been subjected to fluctuations in the context of the COVID-19 pandemic. Country-level virus prevalence and geography conditions added complexity to understanding atmospheric GHG accumulation sensitivities in terms of the growth rate. Here, extensive data sets were comprehensively analyzed to capture historical and projected fate of atmospheric GHG concentrations.
View Article and Find Full Text PDFGlobal prioritization schemes vary in their impact on the placement of protected areas.
PLoS One
January 2025
Department of Forest Resources Management, University of British Columbia, Vancouver, British Columbia, Canada.
In response to global declines in biodiversity, many global conservation prioritization schemes were developed to guide effective protected area establishment. Protected area coverage has grown dramatically since the introduction of several high-profile biodiversity prioritization schemes, but the impact of such schemes on protected area establishment has not been evaluated. We used matching methods and a Before-After Control-Impact causal analysis to evaluate the impact of two key prioritization schemes-Biodiversity Hotspots and Last of the Wild-representing examples of the reactive and proactive ends of the prioritization spectrum.
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