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L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.
Front Pharmacol
December 2024
Division of Gynecologic Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Introduction: Endometrial cancer is the most common malignancy of the female reproductive system in the United States. is a versatile, nutrient-dense, low-calorie vegetable that contains various bioactive metabolites that have shown a variety of biologic functions beneficial to health. The metabolites from extracts or extracts exhibit significant anti-tumorigenic activity in some pre-clinical models of cancer.
View Article and Find Full Text PDFThe impact of a low-calorie, reduced-fat diet on liver attenuation imaging: a randomized clinical trial.
Abdom Radiol (NY)
December 2024
The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Purpose: To investigate whether a low-calorie, reduced-fat diet affects liver attenuation imaging (ATI) measurements.
Methods: A total of 320 participants were enrolled in this prospective study. They were randomly assigned to four groups: a fasting group, a postprandial 0.
Changes in insulin sensitivity and gut peptides 8 and 52 weeks after bariatric surgery or low-calorie diet.
Clin Obes
December 2024
Human Translational Physiology, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
The endocrine consequences of weight loss by bariatric surgery (BS) and caloric restriction are not fully understood but contribute to variable improvements in insulin sensitivity and cardiometabolic health. This study compared changes in insulin sensitivity and plasma concentrations of gut peptides 8 weeks and 1 year after BS and a low-calorie diet (LCD). Nineteen female patients with obesity self-selected BS (gastric bypass [n = 5] or sleeve gastrectomy [n = 7]) or LCD (n = 7) in this parallel-arm, prospective observational study.
View Article and Find Full Text PDFLong-Term Yo-Yo Dieting Exaggerates Liver Steatosis and Lesions but Preserves Muscle Performance in Male Zebrafish.
Int J Mol Sci
December 2024
Department of Animal Science and Technology, National Taiwan University, Taipei 10672, Taiwan.
Weight regain within one year after weight loss is frequently observed and is referred to as yo-yo dieting or weight cycling. In this study, we explore the effects of yo-yo dieting on the liver, adipose tissue, and muscle characteristics of male zebrafish. Four-month-old AB wild-type male zebrafish were randomly assigned to three groups: high-calorie intake (H, seven meals per day), low-calorie intake (L, two meals per day), and yo-yo diet (the low- and high-calorie alternation switched every two weeks) groups.
View Article and Find Full Text PDFOsmotic Dehydration of Japanese Quince () Fruits in Erythritol Solutions: Impact of Processing Conditions on the Kinetic Parameters and on Physicochemical and Antioxidant Properties of the Fruits.
Molecules
November 2024
Department of Agroecology and Crop Production, University of Agriculture in Krakow, Mickiewicza 21, 31-120 Krakow, Poland.
The present work aimed to evaluate the effectiveness of erythritol as an osmotic agent in the osmotic dehydration (OD) process of Japanese quince fruits and to assess its effects on their physicochemical and antioxidant properties. The efficiency of the OD process was determined by examining its kinetics and comparing the results to those from a sucrose solution. In selected osmotically dehydrated fruits, the following parameters were determined: dry matter content, total acidity, pH, sugar profile, color parameters, total phenolic and flavonoid content, antioxidant activity (DPPH and ABTS assays), and vitamin C content.
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