Preserving breed uniqueness and purity is vitally important in developing conservation/breeding programs for a germplasm collection of rare and endangered chicken breeds. The present study was aimed at analyzing SNP genetic variability of 21 small local and imported purebred and F crossbred populations and identifying crossbreeding events via whole-genome evaluation of runs of homozygosity (ROH). The admixture models more efficiently reflected population structure, pinpointing crossbreeding events in the presence of ancestral populations but not in their absence. Multidimensional scaling and -based analyses did not discriminate properly between purebred populations and F crossbreds, especially when comparing related breeds. When applying the ROH-based approach, more and longer ROHs were revealed in purebred individuals/populations, suggesting this as an effective implement in genome-wide analysis of germplasm breed purity.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602725 | PMC |
| http://dx.doi.org/10.3390/ani10101887 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for bone fragility.
Elife
January 2025
Center for Medical Genetics Ghent, Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Heritable fragile bone disorders (FBDs), ranging from multifactorial to rare monogenic conditions, are characterized by an elevated fracture risk. Validating causative genes and understanding their mechanisms remain challenging. We assessed a semi-high throughput zebrafish screening platform for rapid in vivo functional testing of candidate FBD genes.
View Article and Find Full Text PDFGenetic and Structural Factors Contributing to the Dominance and Persistence of Goose Astrovirus Type 2.
Avian Pathol
January 2025
College of Animal Science and Technology/Veterinary Medicine, Anhui Agricultural University, Hefei, PR China.
Goose astrovirus (GoAstV) has emerged as a significant pathogen affecting the goose industry in China, with GoAstV-2 becoming the dominant genotype since 2017. This study explores the genetic and structural factors underlying the prevalence of GoAstV-2, focusing on codon usage bias, spike protein variability, and structural stability. Phylogenetic and effective population size analyses revealed that GoAstV-2 experienced rapid expansion between 2017 and 2018, followed by population stabilization.
View Article and Find Full Text PDFSelection of Nonlethal Early Biomarkers to Predict Gilthead Seabream () Growth.
Aquac Nutr
January 2025
Department of Animal Science, Laboratory of Applied Hydrobiology, Agricultural University of Athens, Iera Odos 75 11855, Athens, Greece.
One of the main challenges in aquaculture is the constant search for sustainable alternative feed ingredients that can successfully replace fishmeal (FM) without any negative effects on fish growth and health. The goal of the present study was to develop a toolbox for rapidly anticipating the dynamics of fish growth following the introduction of a new feed; nonlethal, biochemical, and molecular markers that provide insights into physiological changes in the fish. A nutritional challenge by feeding a conventional feed rich in FM protein (FM diet) versus an experimental feed rich in plant protein (PP) and low FM inclusion (PP diet), in 20 different families of gilthead sea bream () was performed.
View Article and Find Full Text PDFClinical use of molecular methods for infection in endemic and non-endemic countries: Benefits, limitations and challenges.
Front Parasitol
November 2023
Drugs for Neglected Diseases initiative, Latin America, Rio de Janeiro, Brazil.
infection is diagnosed by parasitological, molecular, and serological tests. Molecular methods based on DNA amplification provide a more sensitive alternative to classical parasitological techniques for detecting evidence of parasitemia, and are the preferred tests for congenital and oral transmission cases and parasite reactivation in chronically infected immunosuppressed individuals. In newborns at risk of vertical transmission, simplified diagnostic algorithms that provide timely results can reduce the high follow-up losses observed with current algorithms.
View Article and Find Full Text PDFDevelopment of Self-Concept in Childhood and Adolescence: How Neuroscience Can Inform Theory and Vice Versa.
Hum Dev
December 2024
Erasmus School of Social and Behavioral Sciences, Erasmus University Rotterdam, Rotterdam, The Netherlands.
How do we develop a stable and coherent self-concept in contemporary times? Susan Harter's original work, (1999; 2012), argues that cognitive and social processes are building blocks for developing a coherent sense of self, resulting in self-concept clarity across various domains in life (e.g., [pro-]social, academic, and physical).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!