Photonic crystal based biosensors: Emerging inverse opals for biomarker detection.

Talanta

Photonics Group, Research Institute for Applied Physics and Astronomy, University of Tabriz, Tabriz, Iran; Department of Physics, Engineering Physics & Astronomy, Queen's University, Kingston, Ontario, Canada.

Published: January 2021

Photonic crystal (PC)-based inverse opal (IO) arrays are one of the substrates for label-free sensing mechanism. IO-based materials with their advanced and ordered three-dimensional microporous structures have recently found attractive optical sensor and biological applications in the detection of biomolecules like proteins, DNA, viruses, etc. The unique optical and structural properties of IO materials can simplify the improvements in non-destructive optical study capabilities for point of care testing (POCT) used within a wide variety of biosensor research. In this review, which is an interdisciplinary investigation among nanotechnology, biology, chemistry and medical sciences, the recent fabrication methodologies and the main challenges regarding the application of (inverse opals) IOs in terms of their bio-sensing capability are summarized.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466948PMC
http://dx.doi.org/10.1016/j.talanta.2020.121615DOI Listing

Publication Analysis

Top Keywords

photonic crystal
8
inverse opals
8
crystal based
4
based biosensors
4
biosensors emerging
4
emerging inverse
4
opals biomarker
4
biomarker detection
4
detection photonic
4
crystal pc-based
4

Similar Publications

A novel helically twisted photonic crystal fiber (PCF) is designed and proposed for sensing toxic gases with refractive indices ranging from 1.00 to 1.08.

View Article and Find Full Text PDF

Bending loss is one of the serious problems for constructing nanophotonic integrated circuits. Recently, many works reported that valley photonic crystals (VPhCs) enable significantly high transmission via 120-degree sharp bends. However, it is unclear whether the high bend-transmission results directly from the valley-photonic effects, which are based on the breaking of inversion symmetry.

View Article and Find Full Text PDF

Objective: Timing calibration is essential for positron emission tomography (PET) system as it enhances timing resolution to improve image quality. Traditionally, positron sources are employed for timing calibration. However, the photons emitted by these sources travel in opposite directions, necessitating that positrons annihilate at multiple locations to collect coincidence data across a greater number of lines of response (LORs).

View Article and Find Full Text PDF

Improving timing resolution of BGO for TOF-PET: a comparative analysis with and without deep learning.

EJNMMI Phys

January 2025

Sherbrooke Molecular Imaging Center and Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, 12th Avenue N, Sherbrooke, J1H 5N4, Québec, Canada.

Background: The renewed interest in BGO scintillators for TOF-PET is driven by the improved Cherenkov photon detection with new blue-sensitive SiPMs. However, the slower scintillation light from BGO causes significant time walk with leading edge discrimination (LED), which degrades the coincidence time resolution (CTR). To address this, a time walk correction (TWC) can be done by using the rise time measured with a second threshold.

View Article and Find Full Text PDF

Optofluidic paper-based analytical device for discriminative detection of organic substances via digital color coding.

Microsyst Nanoeng

January 2025

Department of Chemical and Biomolecular Engineering, Chonnam National University, 50 Daehak-ro, Yeosu-si, Jeollanam-do, 59626, Republic of Korea.

Developing a portable yet affordable method for the discrimination of chemical substances with good sensitivity and selectivity is essential for on-site visual detection of unknown substances. Herein, we propose an optofluidic paper-based analytical device (PAD) that consists of a macromolecule-driven flow (MDF) gate and photonic crystal (PhC) coding units, enabling portable and scalable detection and discrimination of various organic chemical, mimicking the olfactory system. The MDF gate is designed for precise flow control of liquid analytes, which depends on intermolecular interactions between the polymer at the MDF gate and the liquid analytes.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!