Time-efficient hearing tests are important in both clinical practice and research studies. This particularly applies to notched-noise tests, which are rarely done in clinical practice because of the time required. Auditory-filter shapes derived from notched-noise data may be useful for diagnosis of the cause of hearing loss and for fitting of hearing aids, especially if measured over a wide range of center frequencies. To reduce the testing time, we applied Bayesian active learning (BAL) to the notched-noise test, picking the most informative stimulus parameters for each trial based on nine Gaussian Processes. A total of 11 hearing-impaired subjects were tested. In 20 to 30 min, the test provided estimates of signal threshold as a continuous function of frequency from 500 to 4000 Hz for nine notch widths and for notches placed both symmetrically and asymmetrically around the signal frequency. The thresholds were found to be consistent with those obtained using a 2-up/1-down forced-choice procedure at a single center frequency. In particular, differences in threshold between the methods did not vary with notch width. An independent second run of the BAL test for one notch width showed that it is reliable. The data derived from the BAL test were used to estimate auditory-filter width and asymmetry and detection efficiency for center frequencies from 500 to 4000 Hz. The results agreed with expectations for cochlear hearing losses that were derived from the audiogram and a hearing model.
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http://dx.doi.org/10.1177/2331216520952992 | DOI Listing |
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School of Mechanical Engineering, Purdue University, 585 Purdue Mall, West Lafayette, IN, 47907, USA.
Multi-photon polymerization is a well-established, yet actively developing, additive manufacturing technique for 3D printing on the micro/nanoscale. Like all additive manufacturing techniques, determining the process parameters necessary to achieve dimensional accuracy for a structure 3D printed using this method is not always straightforward and can require time-consuming experimentation. In this work, an active machine learning based framework is presented for determining optimal process parameters for the recently developed, high-speed, layer-by-layer continuous projection 3D printing process.
View Article and Find Full Text PDFSci Total Environ
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HEOA - West China Health & Medical Geography Group, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610044, China; Institute for Healthy Cities and West China Research Centre for Rural Health Development, West China-PUMC C.C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan 610044, China. Electronic address:
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View Article and Find Full Text PDFBMC Public Health
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College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua, China.
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J Physiol
January 2025
Department of Biological Science, Programs in Neuroscience, Molecular Biophysics and Cell and Molecular Biology, Florida State University, Tallahassee, Florida, USA.
Eating behaviours are influenced by the integration of gustatory, olfactory and somatosensory signals, which all contribute to the perception of flavour. Although extensive research has explored the neural correlates of taste in the gustatory cortex (GC), less is known about its role in encoding thermal information. This study investigates the encoding of oral thermal and chemosensory signals by GC neurons compared to the oral somatosensory cortex.
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