AI Article Synopsis
- * Key compounds identified include prenylated phenylpropanoids and caffeoyl-quinic acids, along with various flavonols.
- * Less polar extracts exhibited stronger anti-mycoplasma activity compared to more polar alcoholic and aqueous extracts, suggesting Itapará propolis could be a valuable resource for drug development.
Article Abstract
Extracts of a sample of brown propolis produced in the district of Itapará (Southern Brazil) were obtained with solvents with increasing polarity. The extracts were analyzed by RPHPLC-DAD-ESI-MS/MS and evaluated toward activity against , , , , , and . Typical components of "alecrim-do-campo" propolis (e.g. prenylated phenylpropanoids and caffeoyl-quinic acids) were characterized in the analyzed extraccts, in addition to several flavonols. Less polar extracts showed higher anti-mycoplasma activity (MIC value commonly 3.9 μg/mL) than alcoholic and aqueous extracts (MIC value often 7.8-250 μg/mL). The results indicate that Itapará propolis is a promising source for the development of therapeutic drugs.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520391 | PMC |
| http://dx.doi.org/10.1007/s13197-020-04461-y | DOI Listing |
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