Pomegranate peel has substantial amounts of phenolic compounds, such as hydrolysable tannins (punicalin, punicalagin, ellagic acid, and gallic acid), flavonoids (anthocyanins and catechins), and nutrients, which are responsible for its biological activity. However, during processing, the level of peel compounds can be significantly altered depending on the peel processing technique used, for example, ranging from 38.6 to 50.3 mg/g for punicalagins. This review focuses on the influence of postharvest processing factors on the pharmacological, phytochemical, and nutritional properties of pomegranate ( L.) peel. Various peel drying strategies (sun drying, microwave drying, vacuum drying, and oven drying) and different extraction protocols (solvent, super-critical fluid, ultrasound-assisted, microwave-assisted, and pressurized liquid extractions) that are used to recover phytochemical compounds of the pomegranate peel are described. A total phenolic content of 40.8 mg gallic acid equivalent (GAE)/g DM was recorded when sun drying was used, but the recovery of the total phenolic content was higher at 264.3 mg TAE/g when pressurised liquid extraction was performed. However, pressurised liquid extraction is costly due to the high initial investment costs and the limited possibility of carrying out selective extractions of organic compounds from complex peel samples. The effects of these methods on the phytochemical profiles of pomegranate peel extracts are also influenced by the cultivar and conditions used, making it difficult to determine best practice. For example, oven drying at 60 °C resulted in higher levels of punicalin of 888.04 mg CE/kg DM compared to those obtained 40 °C of 768.11 mg CE/kg DM for the Wonderful cultivar. Processes that are easy to set up, cost-effective, and do not compromise the quality and safety aspects of the peel are, thus, more desirable. From the literature survey, we identified a lack of studies testing pretreatment protocols that may result in a lower loss of the valuable biological compounds of pomegranate peels to allow for full exploitation of their health-promoting properties in potentially new value-added products.
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http://dx.doi.org/10.3390/molecules25204690 | DOI Listing |
Int J Biol Macromol
January 2025
Department of Food and Agricultural Products, Food Technology and Agricultural Products Research Center, Standard Research Institute (SRI), PO Box 31745-139, Karaj, Iran.
Walnut husk extract (WHE) and pomegranate peel extract (PPE) were produced through ultrasound-assisted extraction. Total phenol, flavonoid and tannin contents (TPC, TFC and TTC), antioxidant and antimicrobial activities were determined. The best extracts were used for production of alginate (Alg) and chitosan (CS)-coated nanoemulsions containing WHE (NWHE) or PPE (NPPE).
View Article and Find Full Text PDFLife (Basel)
January 2025
Department of Microbiology, Faculty of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Turkey.
Sepsis is a clinical condition causing tissue damage as a result of infection and an exaggerated immune response. Sepsis causes 11 million deaths annually, a third of which are associated with acute lung injury (ALI). Rapid and effective treatment is crucial to improve survival rates.
View Article and Find Full Text PDFAntioxidants (Basel)
January 2025
Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.
Agricultural food waste and by-products could provide high-value compounds that positively affect human and environmental health, thus representing promising ingredients for cosmeceutical products. This study explores the biological activities of tomato skin (HP) and pomegranate peel (PPE) extracts on oral mucosa to evaluate their possible use in mouthwashes. The biological activities of the extracts and the mouthwash (MW) containing them were evaluated in Human Primary Gingival Epithelial cells (HGECs).
View Article and Find Full Text PDFPLoS One
January 2025
Department of Food Science and Nutrition, Ethiopian Institute of Agricultural Research, Shashemene, Ethiopia.
Pomegranate peel powder is used as a functional ingredient in the development of nutritional bars. Pomegranate (Punica granatum) is well known fruit belongs to punicaceae family having multiple health benefits, not only limited to its edible parts but also in its non-edible parts mostly the peel. Fruit wastes are rich source of nutrients, and can be used for the development of functional food products.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Food Nanotechnology, Research Institute of Food Science and Technology (RIFST), Mashhad, PO Box: 91895-157-356, Iran. Electronic address:
The objective of this research is to develop a natural macromolecules-based smart double-layer film using carboxymethyl cellulose (CMC) film containing pomegranate peel anthocyanins (PPA) and cellulose acetate nanofibers (CANFs) with Artemisia sieberi Besser essential oil-loaded nanostructured lipid carriers (ABNLCs). Based on the performance as a color indicator, and other studied properties, the CMC/PPA 8 % film was selected as the optimized film. The double-layer film was constructed by electrospinning the CANFs containing ABNLCs on the optimized CMC film.
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