AI Article Synopsis

  • The study aimed to explore how chronic rhinosinusitis (CRS) affects quality of life (QoL) differently in men and women, particularly in those with nasal polyps (CRSwNP) and aspirin-exacerbated respiratory disease (AERD).
  • A total of 105 patients were analyzed (59 with CRSwNP and 46 with AERD) using the Sino-Nasal Outcome Test-20 to assess QoL and polyp severity.
  • Results showed no significant differences in QoL or polyp scores between male and female patients, indicating that CRS severely impacts QoL in all affected individuals, regardless of sex.

Article Abstract

Purpose: While the overall impact of chronic rhinosinusitis (CRS) on patients' health is diverse, many affected individuals have a substantially impaired quality of life (QoL). The aim of this study was to evaluate the impact of sex-associated differences specifically in the subgroups of CRS with nasal polyps (CRSwNP) and aspirin-exacerbated respiratory disease (AERD) by assessing QoL parameters in women and men separately.

Methods: In a retrospective single-center study, 59 patients with CRSwNP (39 males and 20 females) and 46 patients with AERD (18 males and 28 females) were included. Patient-reported outcome measures (PROM) evaluating QoL via the Sino-Nasal Outcome Test-20 German Adapted Version (SNOT-20 GAV) as well as the total polyp score (TPS) were analysed.

Results: There was no significant difference in TPS (p = 0.5550) and total SNOT-20 GAV scores (p = 0.0726) between male or female patients with CRSwNP or AERD. Furthermore, no significant sex differences were found within disease groups regarding the subcategories of the SNOT-20 GAV items.

Conclusion: Thus, quality of life is severely impaired in patients suffering from various forms of CRS regardless of their sex.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057986PMC
http://dx.doi.org/10.1007/s00405-020-06418-5DOI Listing

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