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Embracing the Future of Clinical Trials in Radiotherapy: An NRG Oncology CIRO Technology Retreat Whitepaper on Pioneering Technologies and AI-Driven Solutions.
Int J Radiat Oncol Biol Phys
January 2025
National Cancer Institute, Bethesda, MD. Electronic address:
This white paper examines the potential of pioneering technologies and artificial intelligence (AI)-driven solutions in advancing clinical trials involving radiotherapy. As the field of radiotherapy evolves, the integration of cutting-edge approaches such as radiopharmaceutical dosimetry, FLASH radiotherapy, image-guided radiation therapy (IGRT), and AI promises to improve treatment planning, patient care, and outcomes. Additionally, recent advancements in quantum science, linear energy transfer/relative biological effect (LET/RBE), and the combination of radiotherapy and immunotherapy create new avenues for innovation in clinical trials.
View Article and Find Full Text PDFIntegration of 168,000 samples reveals global patterns of the human gut microbiome.
Cell
January 2025
Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA. Electronic address:
The factors shaping human microbiome variation are a major focus of biomedical research. While other fields have used large sequencing compendia to extract insights requiring otherwise impractical sample sizes, the microbiome field has lacked a comparably sized resource for the 16S rRNA gene amplicon sequencing commonly used to quantify microbiome composition. To address this gap, we processed 168,464 publicly available human gut microbiome samples with a uniform pipeline.
View Article and Find Full Text PDFThe Future of Artificial Intelligence in Mental Health Nursing Practice: An Integrative Review.
Int J Ment Health Nurs
February 2025
Institute of Health and Allied Professions, Nottingham Trent University, Nottingham, UK.
Artificial intelligence (AI) has been increasingly used in delivering mental healthcare worldwide. Within this context, the traditional role of mental health nurses has been changed and challenged by AI-powered cutting-edge technologies emerging in clinical practice. The aim of this integrative review is to identify and synthesise the evidence of AI-based applications with relevance for, and potential to enhance, mental health nursing practice.
View Article and Find Full Text PDFA lightweight prosthetic hand with 19-DOF dexterity and human-level functions.
Nat Commun
January 2025
Institute of Humanoid Robots, School of Engineering Science, University of Science and Technology of China, Hefei, 230026, China.
A human hand has 23-degree-of-freedom (DOF) dexterity for managing activities of daily living (ADLs). Current prosthetic hands, primarily driven by motors or pneumatic actuators, fall short in replicating human-level functions, primarily due to limited DOF. Here, we develop a lightweight prosthetic hand that possesses biomimetic 19-DOF dexterity by integrating 38 shape-memory alloy (SMA) actuators to precisely control five fingers and the wrist.
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