The future and benefits of mosaic landscapes have been a source of scientific and societal concern due to increasing population growth, climate change, urbanization, and expanding agricultural commodities. There is a growing call for integrated landscape approaches in which landscape actors discuss trade-offs between different land uses with a view to reaching a negotiated decision on the allocation of land uses. Yet, the operationalization of such approaches is still in its infancy, and integrated methodologies to visualize actors' landscape visions are still scarce. This study therefore presents a participatory spatial scenario-building methodology that uncovers local perceptions of landscape dynamics and needed actions in a mixed cocoa-oil-palm landscape in Ghana's Eastern Region. The methodology visualizes landscape actors' perceived plausible changes and desired future landscapes, and is designed to trigger discussions on actions needed to achieve these desired futures. Findings show that farmers and institutional actors are aware of their landscapes with future preferences coming close to actual landscape composition and spatial configuration, and that-contrary to common assumptions-only those in the oil-palm-dominated landscape who already experienced the drawbacks of increasing landscape homogenization desire a mosaic landscape. The paper concludes that the collective mapping process makes actors aware of challenges at landscape level and increases farmers' negotiation power through active engagement in the process and visualization of their knowledge and visions. Application of the methodology requires dedicated funding, political will, and capacity to apply it as an ongoing process, as well as monitoring feedback loops.
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http://dx.doi.org/10.1007/s00267-020-01368-4 | DOI Listing |
JMIR Res Protoc
January 2025
Department of Pediatrics, School of Medicine, University of Virginia, Charlottesville, VA, United States.
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View Article and Find Full Text PDFJ Med Internet Res
January 2025
Tobacco Settlement Endowment Trust Health Promotion Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences, Oklahoma City, OK, United States.
Background: Social behavioral research studies have increasingly shifted to remote recruitment and enrollment procedures. This shifting landscape necessitates evolving best practices to help mitigate the negative impacts of deceptive attempts (eg, fake profiles and bots) at enrolling in behavioral research.
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J Med Internet Res
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Department of Physical Medicine and Rehabilitation, Korea University Anam Hospital, Seoul, Republic of Korea.
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View Article and Find Full Text PDFPLoS One
January 2025
Special Infectious Agents Unit-BSL3, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
The ongoing increase in the prevalence and mutation rate of the influenza virus remains a critical global health issue. A promising strategy for antiviral drug development involves targeting the RNA-dependent RNA polymerase, specifically the PB2-cap binding domain of Influenza A H5N1. This study employs an in-silico approach to inhibit this domain, crucial for viral replication, using potential inhibitors derived from marine bacterial compounds.
View Article and Find Full Text PDFActa Crystallogr B Struct Sci Cryst Eng Mater
February 2025
Department of Chemical Engineering, Sargent Centre for Process Systems Engineering, Institute for Molecular Science and Engineering, Imperial College London, London SW7 2AZ, United Kingdom.
We present an approach to reduce this computational cost substantially, based on the partitioning of the molecule into geometrically separated torsional groups, with the dependence of the intramolecular energy and atomic point charges and dependent degrees of freedom on molecular conformation being computed as a linear combination of the contributions of these groups. This can lead to large savings in computational cost without a significant impact on accuracy, as demonstrated in the cases of N-acetyl-para-aminophenol (paracetamol) and methyl 4-hydroxybenzoate (methyl paraben). The approach is also applied successfully to two larger molecules, benzyl [4-(4-methyl-5-[(4-methylphenyl)sulfonyl]-1,3-thiazol-2-yl)phenyl]carbamate (molecule XX from the fifth CSP blind test) and (2S)-2-[4-(3-fluorobenzyloxy)benzylamino]propionamide (safinamide), for which we conduct the first reported CSP study.
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