AI Article Synopsis
- The study evaluated adherence to tuberculosis prevention in infants using a urine dipstick test for isoniazid metabolites in Kenya.
- Out of 155 tests on 97 infants, nearly 50% showed positive results, despite caregivers claiming adherence.
- Factors like maternal education, controlled HIV status, and no missed medication doses in the last three days were linked to better adherence.
Article Abstract
We assessed adherence in an infant tuberculosis prevention trial in Kenya with a urine isoniazid metabolite-detecting dipstick. Ninety-seven infants had 155 assays performed; 77 (49.7%) were found to be positive despite caregiver-reported adherence. Positive assays were associated with maternal secondary education, HIV suppression and no reported missed doses in past 3 days, suggesting caregiver education and self-medication use influenced infant adherence.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336467 | PMC |
| http://dx.doi.org/10.1097/INF.0000000000002936 | DOI Listing |
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