Image clustering remains challenging when handling image data from heterogeneous sources. Fusing the independent and complementary information existing in heterogeneous sources together facilitates to improve the image clustering performance. To this end, we propose a joint learning framework of multi-view image data fusion and clustering based on nuclear norm minimization. Specifically, we first formulate the problem as matrix factorization to a shared clustering indicator matrix and a representative coefficient matrix. The former is constrained with orthogonality and nonnegativity, which ensures the validation of clustering assignments. The latter is imposed with nuclear norm minimization to achieve compression of principal components for performance improvement. Then, an alternating minimization strategy is employed to efficiently decompose the multi-variable optimization problem into several small solvable sub-problems with closed-form solutions. Extensive experimental results on real-world image and video datasets demonstrate the superiority of proposed method over other state-of-the-art methods.
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http://dx.doi.org/10.1109/TIP.2020.3029883 | DOI Listing |
Sci Rep
December 2024
Department of Electricity and Energy, Selcuk University, Konya, Turkey.
microRNAs (miRNAs) are non-coding RNA molecules that influence the development and progression of many diseases. Research have documented that miRNAs have a significant role in the prevention, diagnosis, and treatment of complex human diseases. Recently, scientists have devoted extensive resources to attempting to find the connections between miRNAs and diseases.
View Article and Find Full Text PDFChem Sci
December 2024
Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan National Laboratory for Optoelectronics, Wuhan Institute of Physics and Mathematics, Innovation Academy of Precision Measurement, Chinese Academy of Sciences Wuhan 430071 China
Proteins typically adopt a single fold to carry out their function, but metamorphic proteins, with multiple folding states, defy this norm. Deciphering the mechanism of conformational interconversion of metamorphic proteins is challenging. Herein, we employed nuclear magnetic resonance (NMR), circular dichroism (CD), and all-atom molecular dynamics (MD) simulations to elucidate the mechanism of fold switching in proteins GA95 and GB95, which share 95% sequence homology.
View Article and Find Full Text PDFPLoS Genet
December 2024
Earlham Institute, Norwich Research Park, Norwich, United Kingdom.
The translation of nucleotide sequences into amino acid sequences, governed by the genetic code, is one of the most conserved features of molecular biology. The standard genetic code, which uses 61 sense codons to encode one of the 20 standard amino acids and 3 stop codons (UAA, UAG, and UGA) to terminate translation, is used by most extant organisms. The protistan phylum Ciliophora (the 'ciliates') are the most prominent exception to this norm, exhibiting the grfeatest diversity of nuclear genetic code variants and evidence of repeated changes in the code.
View Article and Find Full Text PDFPediatr Rheumatol Online J
November 2024
Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences (IKOM), Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Background: With increasing focus on patient-reported outcome measures (PROMs) in chronic rheumatic diseases, we aimed to evaluate the self-reported physical and psychosocial health in children with juvenile idiopathic arthritis (JIA) compared to matched population-based controls. Furthermore, we aimed to study the association of patient- and physician-reported outcome measures in JIA with patient-reported physical disability.
Methods: We used data from a Norwegian JIA cohort study (NorJIA), including clinical characteristics and outcome measures in participants with JIA and sex- and age-matched population-based controls.
J Phys Act Health
January 2025
Institute of Psychology, SWPS University, Wroclaw, Poland.
Background: The social environment is important to consider for effective promotion of movement behaviors like increased physical activity (PA) and reduced sedentary behavior (SB); yet, it is less often considered than individual and built environments. One way to advance social environment research is to develop system maps, an innovative, participatory, action-oriented research process that actively engages stakeholders to visualize system structures and explore how systems "work." The purpose of this research was to develop PA and SB system maps of the social environment embedded within the core/nuclear family system.
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