[This corrects the article DOI: 10.1371/journal.pgen.1007888.].
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http://dx.doi.org/10.1371/journal.pgen.1009139 | DOI Listing |
Alzheimers Dement (Amst)
January 2025
Neurochemistry Laboratory Department of Laboratory Medicine Amsterdam UMC Amsterdam The Netherlands.
Introduction: Blood-based glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), and phosphorylated tau (pTau) have shown promising prognostic potential in Alzheimer's disease (AD), but their applicability in clinical settings where comorbidities are prevalent remains uncertain.
Methods: Simoa assays quantified GFAP, NfL, and pTau181 in retrospectively retrieved prediagnostic serum samples from 102 AD patients and 21 non-AD controls.
Results: Higher serum GFAP levels predicted earlier clinical presentation and faster subsequent Mini-Mental State Examination decline in AD patients.
Front Endocrinol (Lausanne)
January 2025
Department of Gynecology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Patients with adenomyosis not only experience a decrease in quality of life as a result of dysmenorrhea and severe monthly flow but they are also rendered infertile. Pregnancy rates are still low among women with adenomyosis, even with assisted reproduction. According to the current study, endometrial receptivity is primarily responsible for the lower conception rate among patients with adenomyosis.
View Article and Find Full Text PDFSci Rep
January 2025
Program in Biochemistry, Mount Holyoke College, South Hadley, MA, 01075, USA.
We have previously developed a transcription-based bacterial three-hybrid (B3H) assay as a genetic approach to probe RNA-protein interactions inside of E. coli cells. This system offers a straightforward path to identify and assess the consequences of mutations in RBPs with molecular phenotypes of interest.
View Article and Find Full Text PDFSci Rep
January 2025
Faculty of Medicine of Tunis - LR99ES09 Research Laboratory «Antimicrobial Resistance», University of Tunis El Manar, 1007, Tunis, Tunisia.
NPJ Parkinsons Dis
January 2025
Movement Disorders Unit, Department of Neurology, Hospital La Fe, Valencia, Spain.
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