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| http://dx.doi.org/10.1002/lt.25921 | DOI Listing |
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Impact of Lookback Duration on the Performance of a Claims-Based Frailty Proxy in Women With Stage I-III Breast Cancer.
Pharmacoepidemiol Drug Saf
February 2025
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Background: Frailty is an important prognostic indicator in older women with breast cancer. The Faurot frailty index, a validated claims-based frailty proxy measure, uses healthcare billing codes during a user-specified ascertainment window to predict frailty. We assessed how the duration of frailty ascertainment affected the ability of the Faurot frailty index to predict one-year mortality in women with stage I-II breast cancer.
View Article and Find Full Text PDFFrailty in older adults with systemic lupus erythematosus and emergency department utilization: an administrative claims data analysis of Medicare beneficiaries.
Clin Rheumatol
December 2024
Division of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
Introduction / Objectives: While presence of concomitant SLE and frailty has been associated with greater emergency department (ED) use than SLE alone in young/mid-aged adults, whether frailty increases ED use in older adults with SLE remains unknown. In a nationally representative United States administrative claims dataset, we investigated the association of frailty duration with use of ED services in the SLE population compared with individuals without systemic rheumatic disease (SRD).
Method: We identified Medicare beneficiaries ≥ 65 years with SLE and matched them (1:4) by age and gender with non-SRD comparators with osteoarthritis.
Frailty, social deprivation, and mortality among Medicare fee-for-service beneficiaries.
J Am Geriatr Soc
December 2024
Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.
Background: The geographic distribution of frailty and social deprivation, and their association with mortality in the United States, have not been well studied.
Methods: We estimated claims-based frailty index (CFI) (range: 0-1) and area-level social deprivation index (SDI) (range: 0-100) in a 5% random sample of 1,207,323 Medicare fee-for-service beneficiaries 65 years and older. We examined the prevalence of frailty (defined as CFI ≥ 0.
The relationship between anticholinergic burden and frailty in the year preceding a diagnosis of dementia with Lewy bodies.
Alzheimers Dement (Amst)
December 2024
Introduction: Little is known regarding the relationship between anticholinergic medications and frailty in dementia with Lewy bodies (DLB).
Methods: Anticholinergic Cognitive Burden Scale (ACB) and Claims-based Frailty Index scores were calculated for 12 months prior to the dementia diagnosis using electronic medical record and claims data. Logistic regression was used to estimate the association between ACB and odds of frailty.
Rates and predictors of opioid deprescribing after fracture: A retrospective study of Medicare fee-for-service claims.
J Am Geriatr Soc
December 2024
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Article Synopsis
- - The study focuses on opioid discontinuation rates and their predictors among older adults (65+) with Alzheimer's disease-related dementias (ADRD) or frailty who had undergone a fracture and started opioid treatment.
- - It analyzed 33,027 Medicare beneficiaries and found that about 81-83% of non-frail individuals discontinued opioids within 30 days, while those with frailty or ADRD had lower discontinuation rates (76%-77%).
- - Those with both ADRD and frailty were less likely to discontinue opioids compared to those without these conditions, indicating different opioid management needs based on health status.
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