AI Article Synopsis
- * A systematic review found a significant prevalence of depression (27%) and anxiety (28%) among patients with lichen planus, with variations possibly due to geographical and methodological differences.
- * The findings indicate a strong statistical relationship (odds ratio 3.79 for depression and 2.54 for anxiety) and highlight the importance of screening and potential psychiatric referrals for affected patients.
Article Abstract
The association between certain chronic inflammatory skin diseases and psychiatric disorders or conditions has been well documented. However, the exact magnitude of the association between lichen planus and depression/anxiety symptoms and disorders is un-known. A systematic review and pooled meta-analyses were performed to examine the prevalence and odds of depression and anxiety in patients with lichen planus. The meta-analyses showed a high prevalence of signs of depression (27% [19-36%]) and anxiety (28% [21-36%]). The geographical location of the study may partly explain these vari-ations, but method-ological differences could also be involved. Case-control studies showed a strong association between lichen planus and signs of depression (odds ratio 3.79, 95% confidence interval [2.35; 6.12]) or anxiety (odds ratio 2.54, 95% confidence interval [1.73; 3.72]). These results raise the necessity of screening for the presence of depressive and anxiety symptoms or disorders in patients with lichen planus, and of referring such patients for psychiatric evaluation and appropriate treatment, if necessary.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309823 | PMC |
| http://dx.doi.org/10.2340/00015555-3660 | DOI Listing |
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