analysis revealed that a lectin, jacalin from jackfruit seeds, recognizes a glycosylated region of the receptor-binding domain (RBD) of SARS-CoV2. Jacalin binding induces conformational changes in RBD and significantly affects its interaction with human angiotensin-converting enzyme 2. The result may open up exploration of lectin-based strategies against COVID-19.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540766 | PMC |
| http://dx.doi.org/10.1098/rsos.200844 | DOI Listing |
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