Veterinary vaccine banks, also referred to as vaccine stockpiles or vaccine strategic reserves, play an important role in the response to infectious animal diseases, by assisting control of the disease and resilience in recovering from its effects. Vaccine banks have a part to play in both emergencies and control programmes. The concept of vaccine banks was initially established as a countermeasure to an animal disease emergency or outbreak or the introduction of a new disease. They have increasingly been used to prevent important diseases identified by Veterinary Authorities as requiring a well-planned control programme through vaccination. Vaccine banks can consist of physical or virtual reserves, or the maintenance of production capacity. Physical reserves comprise vaccine antigen or readyto-use vaccines. Virtual reserves include inventory management by vaccine manufacturers. Maintenance of production capacity encompasses management of the vaccine seed material, and the maintenance of knowledge by the manufacturers through continued research into the target vaccines. The establishment, maintenance and implementation of vaccine banks depend on a number of prerequisites, which include a strategy for the physical or virtual vaccine stockpile, a legislative framework, regulatory arrangements, effective supply-chain mechanisms and adequate surveillance systems. Through international solidarity, vaccine banks are available and accessible to countries that do not have their own reserves. The World Organisation for Animal Health and European Union vaccine banks perform this task. Moreover, vaccine banks have facilitated access to important public health vaccines, such as rabies vaccines. These issues are discussed below, as well as potential opportunities for public-private partnerships in different aspects of vaccine banks.
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http://dx.doi.org/10.20506/rst.39.2.3105 | DOI Listing |
J Med Internet Res
January 2025
Unitat de Recerca i Innovació, Gerència d'Atenció Primària i a la Comunitat de la Catalunya Central, Institut Català de la Salut, Sant Fruitós de Bages, Spain.
Background: The COVID-19 pandemic reshaped social dynamics, fostering reliance on social media for information, connection, and collective sense-making. Understanding how citizens navigate a global health crisis in varying cultural and economic contexts is crucial for effective crisis communication.
Objective: This study examines the evolution of citizen collective sense-making during the COVID-19 pandemic by analyzing social media discourse across Italy, the United Kingdom, and Egypt, representing diverse economic and cultural contexts.
PLoS One
January 2025
The National Centre of Vaccines and Bioprocessing, King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia.
Methotrexate (MTX) is classified as an antimetabolite. It's commonly used to treat lung cancer. MTX is an immunosuppressant following the above-mentioned mechanism of action due to its poor selectivity.
View Article and Find Full Text PDFVaccines (Basel)
December 2024
Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Background: A goal of mucosal human immunodeficiency virus type 1 (HIV-1) vaccines is to generate mucosal plasma cells producing polymeric IgA (pIgA)-neutralizing antibodies at sites of viral entry. However, vaccine immunogens capable of eliciting IgA neutralizing antibodies (nAbs) that recognize tier 2 viral isolates have not yet been identified.
Methods: To determine if stabilized native-like HIV-1 envelope (Env) trimers could generate IgA nAbs, we purified total IgA and IgG from the banked sera of six rhesus macaques that had been found in a previous study to develop serum nAbs after subcutaneous immunization with BG505.
Infect Ecol Epidemiol
December 2024
Macha Research Trust, Choma, Zambia.
Background: Infectious disease agents pose significant threats to humans, wildlife, and livestock, with rodents carrying a third of these agents, many linked to human diseases. However, the range of pathogens in rodents and the hotspots for disease remain poorly understood.
Aim: This study evaluated the prevalence of viral, bacterial, and parasitic pathogens in rodents in riverine and non-riverine areas in selected districts in Zambia.
PLoS Negl Trop Dis
December 2024
International Vaccine Institute, Seoul, Republic of Korea.
Background: Hepatitis E virus (HEV) causes acute jaundice and poses an important public health problem in low- and middle-income countries. Limited surveillance capacity and suboptimal access to diagnostics leads to under-reporting of HEV infections in affected countries, including Nepal. Serum antibodies against HEV are indicative of past infection.
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