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http://dx.doi.org/10.1039/d0fd90013c | DOI Listing |
Cell-type-specific activation of parvalbumin (PV)-expressing neurons in the external globus pallidus (GPe) through optogenetics has shown promise in facilitating long-lasting movement dysfunction recovery in mice with Parkinson's disease. However, its translational potential is hindered by adverse effects stemming from the invasive implantation of optical fibers into the brain. In this study, we have developed a non-invasive optogenetics approach, utilizing focused ultrasound-triggered mechanoluminescent nanotransducers to enable remote photon delivery deep in the brain for genetically targeted neuromodulation.
View Article and Find Full Text PDFBinocular vision requires that the brain integrate information coming from each eye. These images are combined (fused) to generate a meaningful composite image. Differences between images, within a range, provide useful information about depth (stereopsis).
View Article and Find Full Text PDFACS Mater Au
January 2025
Liquid Crystal Research Laboratory, Department of Physics, University of Lucknow, Lucknow, Uttar Pradesh 226007, India.
Polymer-dispersed liquid crystals (PDLCs) stand at the intersection of polymer science and liquid crystal technology, offering a unique blend of optical versatility and mechanical durability. These composite materials are composed of droplets of liquid crystals interspersed in a matrix of polymeric materials, harnessing the optical properties of liquid crystals while benefiting from the structural integrity of polymers. The responsiveness of LCs combined with the mechanical rigidity of polymers make polymer/LC composites-where the polymer network or matrix is used to stabilize and modify the LC phase-extremely important for scientists developing novel adaptive optical devices.
View Article and Find Full Text PDFCogn Neurodyn
December 2025
State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, #10 Xitucheng Road, Beijing, 100876 People's Republic of China.
The dentate gyrus (DG) in hippocampus is reported to perform pattern separation, converting similar inputs into different outputs and thus avoiding memory interference. Previous studies have found that human and mice with epilepsy have significant pattern separation defects and a portion of adult-born granule cells (abGCs) migrate abnormally into the hilus, forming hilus ectopic granule cells (HEGCs). For the lack of relevant pathophysiological experiments, how HEGCs affect pattern separation remains unclear.
View Article and Find Full Text PDFChem Soc Rev
January 2025
School of Science, RMIT University, Melbourne, 3000, Australia.
Metal halide perovskites (MHPs) have emerged as the most promising materials due to superior optoelectronic properties and great applications spanning from photovoltaics to photonics. Absorption spectroscopy provides a broad and deep insight into the carrier dynamics of MHPs, and is a critical complement to fluorescence and scattering spectroscopy. However, absorption spectroscopy is often misunderstood or underestimated, being seen as UV-vis spectroscopy only, which can lead to various misinterpretations.
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