Objective: The goal of the study is to investigate the association of pertinent preoperative temporal bone computed tomography (CT) and brain magnetic resonance imaging (MRI) results and intraoperative surgical findings and complications of pediatric cochlear implantation reported in academic settings.
Methods: This is a retrospective review of cochlear implant patients who received a pre-operative temporal bone CT and MRI of the brain between 2005 and 2012 at academic pediatric otolaryngology practices within children's hospitals in the United States and France. Scans were reviewed in a double-blind fashion and compared to intraoperative findings.
Results: 91 children were analyzed (mean age 5.54 +/- 0.58 years). A small facial recess identified on CT was associated with difficult insertion of electrodes (= 0.0003). A prominent sigmoid sinus noted on CT was associated of difficult insertion of electrodes (= 0.01), iatrogenic tegmen dehiscence (= 0.005), as well as difficult round window access (= 0.025). No specific CT finding was found to be associated with external auditory canal injury, perilymphatic gusher, or iatrogenic facial nerve injury. MRI brain and internal auditory canal findings were not predictive of surgical outcomes.
Conclusions: Preoperative CT and MRI remain an important planning tool for pediatric cochlear implantation, particularly in academic institutions. The findings of our study demonstrate that a detailed assessment of both preoperative CT and MRI are valuable for teaching and surgical planning.
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http://dx.doi.org/10.1080/14670100.2020.1830239 | DOI Listing |
Acta Otolaryngol
January 2025
Department of Audiology and Prevention of Communication Disorders, All India Institute of Speech and Hearing, Mysuru, Karnataka, India.
Background: Although Cochlear implantation (CI) is effective in restoring hearing for children with severe-to-profound sensorineural hearing loss, it may influence the middle ear mechanics, potentially causing an air-bone gap and altering middle ear stiffness, which is not detected by traditional 226 Hz tympanometry.
Aims/objectives: To investigate the effect of mastoidectomy posterior tympanotomy (MPTA) on wideband absorbance (WBA) in children with CI.
Materials And Methods: The study included 20 normal-hearing children (normal group) and 10 children with CIs who underwent MPTA (CI-MPTA group), aged 3-10 years.
The cochlear nuclear complex (CN), the starting point for all central auditory processing, encompasses a suite of neuronal cell types highly specialized for neural coding of acoustic signals. However, the molecular logic governing these specializations remains unknown. By combining single-nucleus RNA sequencing and Patch-seq analysis, we reveal a set of transcriptionally distinct cell populations encompassing all previously observed types and discover multiple hitherto unknown subtypes with anatomical and physiological identity.
View Article and Find Full Text PDFLaryngoscope
January 2025
Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
Objective: Peripheral bilateral vestibular hypofunction (BVH) is a rare condition that is well-studied in the adult population, whereas characterization in children has been limited. We report a pediatric cohort of patients with BVH at a multidisciplinary, tertiary care pediatric vestibular clinic.
Methods: A record review of 832 patients with balance-related complaints in our center was conducted.
Children (Basel)
December 2024
Department of Audiology, Otology, Neurotology & Cochlear Implant Unit, Athens Pediatric Center, 15125 Athens, Greece.
Neonatal hearing screening (NHS) is a critical public health measure for early identification of hearing loss, ensuring timely access to interventions that can dramatically improve a child's language development, cognitive abilities, and social inclusion. Beyond clinical benefits, NHS provides long-term advantages in education and quality of life. Given that congenital hearing loss affects approximately 1-2 in every 1000 newborns worldwide, the case for universal screening is clear.
View Article and Find Full Text PDFAntioxidants (Basel)
December 2024
Institute of Pharmacology and Toxicology, Paracelsus Medical University, 5020 Salzburg, Austria.
Cisplatin is an established component of treatment protocols for various solid malignancies but carries a significant potential for serious adverse effects. Ototoxicity from cisplatin treatment is an important dose-limiting toxicity that manifests as bilateral, progressive, irreversible, dose-dependent sensorineural hearing loss, ear pain, tinnitus, and vestibular dysfunction. Despite the recent approval of sodium thiosulphate for the prevention of cisplatin-induced hearing loss (CIHL) in pediatric patients, structured prevention programs are not routinely implemented in most hospitals, and reducing platinum-induced ototoxicity in adults remains an important clinical problem without established treatment options.
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