Influence of Ions and pH on the Formation of Solid- and Liquid-like Melanin.

ACS Omega

Photophysics Group, Centre for Molecular Nanometrology, Department of Physics, The Scottish Universities Physics Alliance, University of Strathclyde, John Anderson Building, 107 Rottenrow, Glasgow G4 0NG, U.K.

Published: October 2020

AI Article Synopsis

  • Melanin is a natural pigment that effectively absorbs energy and has a unique macromolecular structure balancing order and disorder.
  • The presence of different ions and variations in pH can significantly affect how melanin forms and its overall structure, even if its absorption properties remain mostly unchanged.
  • Understanding these influences could help in manipulating melanin's structure for new bio-engineering applications while maintaining its valuable optical characteristics.

Article Abstract

Melanin is a natural pigment with broadband absorption and effective ability to dissipate the energy absorbed. The macromolecular structure of melanin shows a delicate balance between short-range ordered and disordered structures without being a random aggregate. The presence of ions or the variation in pH or ionic strength can alter the self-assembly process which subsequently changes the structure of melanin. To understand these relationships, this study investigates the influence of ions and pH in melanin formation. The types of ions present and pH have a profound influence on the formation and structure of melanin particles, while only minor changes are observed in the absorption and excitation-emission analysis. In some conditions, the formation of discernible particles with significant refractive index contrast is avoided while retaining the spectroscopic characteristics of melanin, leading to liquid-like melanin. These findings identify potential pathways which can be used to manipulate the melanin macromolecular structure while providing the desired spectral properties to enable novel bio-engineering applications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542583PMC
http://dx.doi.org/10.1021/acsomega.0c01953DOI Listing

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