AI Article Synopsis
- Air pollution can make people with airway diseases like asthma and allergies very sick and can even lead to death.
- It causes problems in the lungs by increasing inflammation and making infections more likely.
- Scientists studied how pollution affects these diseases and looked into things like blood tests and changes in the airway that happen after being exposed to pollution, especially when someone is also sick.
Article Abstract
Air pollution causes significant morbidity and mortality in patients with inflammatory airway diseases (IAD) such as allergic rhinitis (AR), chronic rhinosinusitis (CRS), asthma, and chronic obstructive pulmonary disease (COPD). Oxidative stress in patients with IAD can induce eosinophilic inflammation in the airways, augment atopic allergic sensitization, and increase susceptibility to infection. We reviewed emerging data depicting the involvement of oxidative stress in IAD patients. We evaluated biomarkers, outcome measures and immunopathological alterations across the airway mucosal barrier following exposure, particularly when accentuated by an infectious insult.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534666 | PMC |
| http://dx.doi.org/10.1016/j.waojou.2020.100467 | DOI Listing |
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