Prepubertal-type teratomas are rare, especially in postpubertal patients. We present a case of a 43-year-old man with a palpable painless mass in the left-sided testis discovered by accident. Scrotal ultrasound and magnetic resonance imaging revealed a 2.7×2.0 cm mass inside the left testis, and malignancy could not be excluded, though classical serum tumor makers were within normal limits. Radical testicular resection was then conducted, and the pathologic report proved the mass to be a testicular epidermoid cyst, a rare form of prepubertal-type teratoma. Relevant published literature is also reviewed in our text.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539878PMC

Publication Analysis

Top Keywords

prepubertal-type teratoma
8
teratoma postpubertal
4
postpubertal patient
4
patient case
4
case report
4
report review
4
review literature
4
literature prepubertal-type
4
prepubertal-type teratomas
4
teratomas rare
4

Similar Publications

Background: Testicular germ cell tumor (TGCT) is the most common type of tumor in young men. Type II germ cell tumors including postpubertal-type teratomas are derived from the germ cell neoplasia in situ (GCNIS), whereas prepubertal-type teratomas arise independently of the GCNIS. The consomic mouse strain 129.

View Article and Find Full Text PDF

Testicular tumors are rare in children, representing a small percentage of pediatric solid tumors, with an incidence of 2 cases per 100,000 males. Teratomas, which are the most prevalent tumors in infants, may manifest in mature, immature, or malignant forms. While mature teratomas are typically found in the abdomen, intratesticular prepubertal-type teratomas in infants are infrequent.

View Article and Find Full Text PDF
Article Synopsis
  • Testicular germ cell tumors (GCT) are split into three types based on how they develop and their characteristics: Type I (prepubertal), Type II, and Type III.
  • Type I usually happens in kids and teens, while Type II comes from non-invasive germ cells and has a specific change on chromosome 12, and Type III happens in older men with changes on chromosome 9.
  • Each type has different types of tumors and requires different treatments, with Type II being more complicated and worse to treat compared to the others.
View Article and Find Full Text PDF

Prepubertal-type teratomas are uncommon, especially in postpubertal male patients. We document a case of a 28-year-old man with a lifelong history of bilateral testicular masses who presented with scrotal fistulas and no clinical evidence of extratesticular disease. Bilateral radical orchiectomies demonstrated large bilateral solid and cystic masses that contained grossly visible hairs.

View Article and Find Full Text PDF
Article Synopsis
  • - Testicular teratomas can appear in both children and adult men, but prognosis varies significantly, with pediatric teratomas usually being benign and occurring mostly before age 4, while adult teratomas often form part of mixed germ cell tumors with higher risk for metastasis.
  • - In rare cases, testicular teratomas can transform into malignant tumors, such as primitive neuroectodermal tumors, which are aggressive and can spread to various locations like the retroperitoneum.
  • - A specific case is highlighted where a patient experienced malignant transformation of a teratoma, leading to metastasis in the mediastinum, and was treated with a combination of surgery and a chemotherapy regimen known as VAC/IE.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!