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A case of anti-laminin γ1 (p200) pemphigoid developed after dipeptidyl peptidase-4 inhibitor administration.
J Dermatol
June 2024
Department of Dermatology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Article Synopsis
- A 73-year-old man with diabetes treated with sitagliptin developed widespread, itchy red skin lesions suspected to be a drug eruption due to the medication.
- Histopathological analysis revealed significant eosinophilic infiltration, leading to the discontinuation of sitagliptin and improvement with treatment, including prednisolone and phototherapy.
- Five months later, he experienced blistering lesions, and further tests indicated he had anti-laminin γ1 pemphigoid, a rare condition linked to the DPP-4 inhibitor, with some supporting autoimmune response findings.
Recurrent Aphthous Stomatitis: An Enigmatic Entity and Sign of Systemic Disease.
Indian J Dermatol
January 2022
Department of Dermatology and Pathology, Rutgers New Jersey Medical School, and Oral Medicine, Rutgers School of Dental Medicine, Newark, New Jersey, USA.
Recurrent aphthous stomatitis (RAS) is a common oral disease characterized by intermittent eruptions of painful oral ulcerations. Hippocrates first described aphthous stomatitis with the Greek word meaning "to inflame." RAS affects 10-20% of the population with the incidence being the highest among young adults.
View Article and Find Full Text PDFColchicine in the treatment of refractory aphthous ulcerations: Review of the literature and two case reports.
Exp Ther Med
March 2021
Department of Pathophysiology, 'Grigore T. Popa' University of Medicine and Pharmacy, 70015 Iasi, Romania.
Colchicine has been known and used for over a millennium for its anti-inflammatory properties, being the treatment of choice for gout and familial Mediterranean fever. A tricyclic alkaloid extracted from the herbaceous plant, , colchicine blocks multiple inflammatory pathways, and has antimitotic and antifibrotic action. Although there are insufficient data on the beneficial mechanism of action, colchicine is a widely used treatment in dermatology, one of the morbid conditions with more evidence of efficacy being recurrent aphthous stomatitis (RAS), a disorder with incompletely known etiopathogenesis and, consequently, with poorly defined treatment.
View Article and Find Full Text PDFOral manifestations of COVID-19 disease: A review article.
Dermatol Ther
January 2021
Leishmaniasis Research Center, Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran.
Dysgeusia is the first recognized oral symptom of novel coronavirus disease (COVID-19). In this review article, we described oral lesions of COVID-19 patients. We searched PubMed library and Google Scholar for published literature since December 2019 until September 2020.
View Article and Find Full Text PDFA herpetiform eruption with unexpected immunofluorescence findings.
Clin Exp Dermatol
January 2021
Department of Pathology, Western General Hospital and The University of Edinburgh, Edinburgh, UK.
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