AI Article Synopsis
- - This study focused on gathering and analyzing both qualitative and quantitative data regarding the diagnosis and management of cannabinoid hyperemesis syndrome (CHS) in adolescents, highlighting its differences from adult cases.
- - Researchers reviewed 1,334 studies, ultimately including 21 relevant articles—10 about diagnosis and 11 on treatment and management.
- - Findings suggest that CHS may be more common in adolescent females, often linked with anxiety and depression, and stress that stopping cannabis use is the only proven effective treatment, despite some symptom relief from medications like haloperidol and topical capsaicin.
Article Abstract
Purpose: This study aimed to synthesize qualitative and quantitative data on the diagnosis and effective management of cannabinoid hyperemesis syndrome (CHS) in the adolescent population.
Methods: Using keywords, 1,334 studies published between December 1954 and December 2019 were extracted from MEDLINE via PubMed, Embase via OVID, CINAHL via EBSCO, Web of Science, and the Cochrane Library. Studies were evaluated by two independent reviewers using predetermined inclusion and exclusion criteria.
Results: The search yielded 148 studies for full-text review, of which 21 were included in this systematic review. A total of 10 articles were related to the diagnosis of CHS, while 11 articles discussed the treatment and management of adolescent cases of CHS.
Conclusions: CHS in the adolescent population fulfills the major and minor diagnostic criteria of CHS in the adult population; however, in adolescent patients, CHS may present more frequently in females, with the earliest reported case presenting at age 15 years. There appears to be a substantial proportion (21%) of adolescent patients diagnosed with CHS that have a history of anxiety and depression; however, higher quality studies to assess the prevalence are warranted. Although haloperidol and topical capsaicin cream may provide symptom relief in isolated cases, complete cessation of cannabis use is currently the only known effective treatment.
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| http://dx.doi.org/10.1016/j.jadohealth.2020.07.035 | DOI Listing |
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