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Review of atypical optic neuritis.
Neurol Sci
December 2024
Institute of Medical Biochemistry, Scientific Research Department, University Clinical Center of Serbia, Belgrade, 11000, Serbia.
Optic neuritis (ON), an inflammatory optic neuropathy, is among the most common causes of visual loss. In its initial clinical appearance, ON may have unilateral or bilateral presentation, and anterior (papillitis) or retrobulbar localization. Traditionally, cases are divided into typical and atypical ON.
View Article and Find Full Text PDFLate Recurrence of C3 Glomerulopathy After SARS-CoV-2 Infection in a Long-Term Kidney Transplant Recipient: A Case Report.
Am J Case Rep
December 2024
Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Roma, Italy.
Article Synopsis
- Kidney transplantation is the best treatment for end-stage kidney disease, but long-term success can be affected by issues like recurrence of native kidney diseases such as C3 glomerulopathy (C3GN).
- A case study documented a female kidney transplant recipient whose kidney function declined after 28 years due to two SARS-CoV-2 infections, alongside evidence of chronic rejection and features of C3GN in her recent biopsy.
- The findings suggest that C3GN may have recurred late in this patient as a result of complement activation triggered by the SARS-CoV-2 infections, indicating a potential new risk factor for post-transplant complications.
C3 glomerulopathy is highly prevalent in French Polynesia.
J Transl Autoimmun
December 2024
Département de Néphrologie et Transplantation d'organes, Centre de Référence des maladies rénales rares, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.
Objective: To compare the natural history of C3 glomerulopathy (C3G) to acute post-infectious glomerulonephritis (APIGN) in a cohort of patients with a relative homogeneity of environment conditions and genetic background.
Methods: We retrospectively reviewed the characteristics of all patients with biopsy proven C3G or APIGN referred in 2013-2019 to the only renal unit in French Polynesia.
Results: Point prevalence of C3G is ∼23 cases per 100,000 inhabitants.
Central Role of CT in Management of Pulmonary Fibrosis.
Radiographics
June 2024
From the Department of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University, Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of Korea (K.J.C.); Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea (H.J.H.); and Department of Radiology (K.J.C., S.M.H., S.K., D.A.L.) and Department of Medicine, Divisions of Pathology (R.D.A.) and Pulmonary and Critical Care Medicine (J.C.C.), National Jewish Health, 1400 Jackson St, Denver, CO 80206.
With the approval of antifibrotic medications to treat patients with idiopathic pulmonary fibrosis and progressive pulmonary fibrosis, radiologists have an integral role in diagnosing these entities and guiding treatment decisions. CT features of early pulmonary fibrosis include irregular thickening of interlobular septa, pleura, and intralobular linear structures, with subsequent progression to reticular abnormality, traction bronchiectasis or bronchiolectasis, and honeycombing. CT patterns of fibrotic lung disease can often be reliably classified on the basis of the CT features and distribution of the condition.
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