A retrospective, single-center analysis of 14 cases of Candida endocarditis (from 355 candidemia cases during the years 2012-2019) revealed a high in-hospital mortality (57.1%), a high proportion of healthcare-associated infections (13/14) and a high treatment preference for echinocandins. Transthoracic echocardiography and F-FDG PET/CT had a sensitivity of 54.5% and 57.1%, respectively. Patients were older than previously described and most patients with Candida endocarditis had persistent candidemia for ≥ 3 days despite antifungal therapy.
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http://dx.doi.org/10.1007/s11046-020-00492-3 | DOI Listing |
J Vasc Surg
January 2025
Department of Surgery, Division of Vascular and Endovascular Surgery, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA. Electronic address:
Objective: Infective endocarditis (IE) is associated with significant morbidity and mortality and places patients at risk for subsequent peripheral vascular emboli. Our goals were to analyze the incidence of peripheral emboli and their associated complications and outcomes.
Methods: A retrospective single-center review of all patients with IE from 2013-2021 was performed.
Case Rep Infect Dis
November 2024
Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar.
Ther Adv Infect Dis
November 2024
Department of Cardiology, AIIMS Jodhpur, Jodhpur, India.
Background: Fungal infective endocarditis (IE) is a rare, yet increasingly recognised condition associated with substantial mortality rates. and are among the notable causative agents, presenting diverse clinical manifestations and complexities in diagnosis and management.
Objectives: This study was undertaken to examine the clinical profiles, diagnostic challenges, treatment modalities, and outcomes of four compelling cases involving and endocarditis.
J Cardiothorac Surg
November 2024
Cardiology Department, Hospital Sírio Libanês, São Paulo, SP, Brasil.
Key Clinical Message: Fungal endocarditis is a rare but potentially fatal infection with significant diagnostic and management challenges. Antifungal therapy and surgical debridement are the preferred treatments in these cases. Antimicrobial therapy with multiple antifungal agents may be required in high-risk patients presenting with prolonged fever suspected of having fungal endocarditis.
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