Non-enzymatic sensor for determination of glucose based on PtNi nanoparticles decorated graphene.

Sci Rep

Shaanxi Provincial Land Engineering Construction Group Co., Ltd.; Institute of Land Engineering and Technology, Shaanxi Provincial Land Engineering Construction Group Co., Ltd.; Key Laboratory of Degraded and Unused Land Consolidation Engineering, the Ministry of Natural Resources, Xi'an, 710075, China.

Published: October 2020

Diabetes has become a universal epidemic in recent years. Herein, the monitoring of glucose in blood is of importance in clinical applications. In this work, PtNi alloy nanoparticles homogeneously dispersed on graphene (PtNi alloy-graphene) was synthesized as a highly effective electrode material for glucose detection. Based on the modified PtNi alloy-graphene/glass carbon (PtNi alloy-graphene/GC) electrode, it is found that the PtNi alloy-graphene/GC electrode exhibited excellent electrocatalytic performance on glucose oxidation. Furthermore, the results from amperometric current-time curve show a good linear range of 0.5-15 mM with the limit of detection of 16 uM (S/N = 3) and a high sensitivity of 24.03 uAmM cm. On account of the good selectivity and durability, the modified electrode was successfully applied on glucose detection in blood serum samples.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545213PMC
http://dx.doi.org/10.1038/s41598-020-73567-2DOI Listing

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